Sorbic Acid

Sorbic Acid

SCHEMBL28069397

C/C=C/C=C/C(=O)O.C=CC(=O)OCCCO

nearest known ligand 0.49

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.49
ALDH1A1 P00352 4/20 0.49
CYP3A4 P08684 2/20 0.49
HPGD P15428 1/20 0.49
HCAR2 Q8TDS4 5/20 0.42
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
HSD17B10 Q99714 1/20 0.41
ATM Q13315 1/20 0.36
THRB P10828 2/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ACHE P22303 1/20 0.30
BACE1 P56817 1/20 0.30
APP P05067 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbic Acid SCHEMBL28172614 0.97 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDHCAR2
Crotonic Acid SCHEMBL28089691 0.89 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDHCAR2
Crotonic Acid SCHEMBL27635748 0.89 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDHCAR2
Fumaric Acid SCHEMBL2774701 0.85 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDHCAR2
Maleic Acid SCHEMBL2774692 0.85 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDHCAR2
Crotonic Acid SCHEMBL21436776 0.84 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDHCAR2
Sorbic Acid SCHEMBL4838388 0.83 TSHR (0.42) TSHRALDH1A1CYP3A4HPGDHCAR2
SCHEMBL28069395 0.82 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDHCAR2
SCHEMBL29132463 0.82 HCAR2 (0.58) TSHRALDH1A1CYP3A4HPGDHCAR2
SCHEMBL9160328 0.82 ATM (0.48) TSHRALDH1A1CYP3A4HPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074724-A Preparation of sorbic acid esters 陶氏环球技术有限责任公司 2017-08-18 CN claimed
CN-107074731-A Preparation of sorbic acid esters 陶氏环球技术有限责任公司 2017-08-18 CN claimed
CN-107074724-A Preparation of sorbic acid esters 陶氏环球技术有限责任公司 2017-08-18 CN disclosed
CN-107074731-A Preparation of sorbic acid esters 陶氏环球技术有限责任公司 2017-08-18 CN disclosed
CN-105985733-A Sorbic acid esters containing coating compositions 陶氏环球技术有限责任公司 2016-10-05 CN disclosed
CN-105647270-A Sorbic acid ester composition 陶氏环球技术有限责任公司 2016-06-08 CN disclosed