Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL2774701 | 1.00 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| SCHEMBL29132463 | 0.96 | HCAR2 (0.58) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| SCHEMBL29185571 | 0.93 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| Acrylic Acid SCHEMBL2973647 | 0.92 | TSHR (0.65) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| Acrylic Acid SCHEMBL28840693 | 0.92 | TSHR (0.65) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| Hydrogen Peroxide SCHEMBL28304846 | 0.92 | TSHR (0.71) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| Maleic Acid SCHEMBL27672360 | 0.90 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| Bicarbonate SCHEMBL27397663 | 0.90 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| SCHEMBL2851828 | 0.90 | TSHR (0.74) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| SCHEMBL26117 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520794-B | Polymerizable composition, photosensitive composition for black matrix, and photosensitive composition for black column spacer | 株式会社艾迪科 | 2025-04-04 | — | — | CN | disclosed |
| WO-2025027985-A1 | COMPOSITION, BLACK MATRIX, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND DISPLAY DEVICE | 株式会社ADEKA | 2025-02-06 | — | — | WO | disclosed |
| CN-110546134-B | Oxime ester compound and photopolymerization initiator containing the same | 株式会社艾迪科 | 2024-12-20 | — | — | CN | disclosed |
| CN-110520796-B | Polymerizable composition, photosensitive composition for black matrix, and photosensitive composition for black column spacer | 株式会社艾迪科 | 2024-11-12 | — | — | CN | disclosed |
| WO-2024202696-A1 | COMPOSITION, BLACK MATRIX, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND DISPLAY DEVICE | 株式会社ADEKA | 2024-10-03 | — | — | WO | disclosed |
| CN-109476773-B | Curable composition, cured product, and method for producing cured product | 株式会社艾迪科 | 2022-05-13 | — | — | CN | disclosed |
| CN-108475019-B | Black photosensitive resin composition | 株式会社艾迪科 | 2022-02-11 | — | — | CN | disclosed |
| CN-112004800-A | Oxime ester compound and photopolymerization initiator containing the same | 株式会社ADEKA | 2020-11-27 | — | — | CN | disclosed |
| CN-111132963-A | Compound, composition, cured product, and method for producing cured product | 株式会社艾迪科 | 2020-05-08 | — | — | CN | disclosed |
| CN-106470971-B | Novel polymerization initiator and radical polymerizable composition containing the same | 株式会社艾迪科 | 2020-03-03 | — | — | CN | disclosed |
| EP-2175320-B1 | ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION | ADEKA CORP (JP) | 2013-03-13 | — | — | EP | disclosed |
| US-8338081-B2 | Alkali-developable photosensitive resin composition and β-diketone compound | ADEKA CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| CN-101546122-B | Color resist composition and a color filter using the same | ADEKA CORP | 2012-11-14 | — | — | CN | disclosed |
| US-20100129753-A1 | ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND BETA-DIKETONE COMPOUND | ADEKA CORPORATION (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-2175320-A1 | ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND -DIKETONE COMPOUND | Adeka Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |
| CN-101546122-A | Color resist composition and a color filter using the same | ASAHI DENKA CO LTD | 2009-09-30 | — | — | CN | disclosed |
| EP-0872529-B2 | BINDER FOR BUILDING STRUCTURES | ASAHI CHEMICAL IND (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-0872529-B1 | BINDER FOR BUILDING STRUCTURES | ASAHI CHEMICAL IND (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6015845-A | Binder for building structure | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0872529-A1 | BINDER FOR BUILDING STRUCTURES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1998-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129753-A1 | ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND BETA-DIKETONE COMPOUND | RPS14, ACAD11, OR10J3 | TSHR 3404/4885ALDH1A1 1770/4885CYP3A4 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.