SCHEMBL28069433

SCHEMBL28069433

Cl[Si](Cl)(Cl)C1=CCCCCC1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.31
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
ALOX15 P16050 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28471659 1.00 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL28472081 1.00 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL28472056 1.00 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL1035563 0.97 KDM1A (0.32) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL4521872 0.90
SCHEMBL17241764 0.81
SCHEMBL7125955 0.79 KDM1A (0.33) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL4272346 0.78 KDM1A (0.30) KDM1A
SCHEMBL299770 0.78 KDM1A (0.30) KDM1A
SCHEMBL28477298 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106831845-B Boron-containing organosilicon compounds, method for the production and use thereof 北京康美特科技股份有限公司 2021-01-26 CN disclosed
CN-106854451-B Sealing agent for solar cell module, and sealing method for solar cell module 北京康美特科技股份有限公司 2020-10-02 CN disclosed
CN-110248724-A Data storage based on nucleic acid 特韦斯特生物科学公司 2019-09-17 CN disclosed
CN-108698012-A Flexible substrates for nucleic acid synthesis 特韦斯特生物科学公司 2018-10-23 CN disclosed
CN-106854451-A Solar cell module sealant, solar cell module and its encapsulating method 北京康美特科技股份有限公司 2017-06-16 CN disclosed
CN-106831845-A Boracic organo-silicon compound, Preparation Method And The Use 北京康美特科技股份有限公司 2017-06-13 CN disclosed
CN-105637097-A De novo synthetic gene library TWIST BIOSCIENCE CORP 2016-06-01 CN disclosed