Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069363 | 0.89 | AKT1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1737441 | 0.83 | HDAC3 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4AKT1 | |
| SCHEMBL28557111 | 0.79 | AKT1 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4AKT1 | |
| SCHEMBL3819098 | 0.79 | AKT1 (0.52) | AKT1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL10423913 | 0.78 | AKT1 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4AKT1 | |
| SCHEMBL1737432 | 0.75 | AKT1 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4AKT1 | |
| SCHEMBL27620369 | 0.75 | MEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27620368 | 0.75 | MEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7324970 | 0.75 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20341352 | 0.75 | AKT1 (0.49) | AKT1HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646284-A | Lacosamide synthesis method | 齐鲁天和惠世制药有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-105646284-A | Lacosamide synthesis method | 齐鲁天和惠世制药有限公司 | 2016-06-08 | — | — | CN | disclosed |