Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 3/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737432 | 0.87 | AKT1 (0.42) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL28557111 | 0.83 | AKT1 (0.38) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL28069482 | 0.83 | PSEN1 (0.40) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL10425083 | 0.83 | CTSK (0.44) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL1577177 | 0.83 | SLC7A5 (0.42) | SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10423913 | 0.82 | AKT1 (0.42) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL10423904 | 0.82 | AKT1 (0.41) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL3819098 | 0.81 | AKT1 (0.52) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL10763383 | 0.79 | — | — | |
| SCHEMBL14935470 | 0.78 | LMNA (0.46) | SLC7A5TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319649-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | EUTICALS GMBH (DE) | 2011-12-29 | — | — | US | claimed |
| EP-2399901-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | Archimica GmbH (DE) | 2011-12-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319649-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | NAAA, MEP1B, BCHE | HDAC3 57/4885HDAC1 270/4885HDAC2 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.