Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805778 | 0.95 | PPARG (0.46) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL2809099 | 0.92 | PPARG (0.42) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL2809209 | 0.81 | EDNRB (0.40) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL6851282 | 0.78 | ALDH1A1 (0.48) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL6851392 | 0.77 | MEN1 (0.63) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL2809106 | 0.76 | PPARG (0.45) | PPARGMAPTMEN1KMT2A | |
| SCHEMBL6856138 | 0.76 | MAPT (0.51) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL2809029 | 0.76 | PPARG (0.50) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL6857667 | 0.74 | MEN1 (0.49) | PPARGMAPTMAPK10MEN1KMT2A | |
| SCHEMBL6857727 | 0.74 | PPARG (0.72) | PPARGMAPTMAPK10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240642-A1 | 1H-Indole-2-Carboxylic Acid Derivatives Useful As PPAR Modulators | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240642-A1 | 1H-Indole-2-Carboxylic Acid Derivatives Useful As PPAR Modulators | PPARD, PPARA, PPARG | PPARG 3/4885MAPT 2916/4885MAPK10 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.