Methanesulfonic Acid Ethyl Ester

Methanesulfonic Acid Ethyl Ester

SCHEMBL28069670

CCOS(C)(=O)=O.Clc1cccc(Cl)c1Cl

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
PTGS2 P35354 1/20 0.38
MCOLN3 Q8TDD5 1/20 0.37
PNMT P11086 1/20 0.36
IDO1 P14902 2/20 0.36
CCR4 P51679 2/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.35
TSHR P16473 3/20 0.35
RECQL P46063 1/20 0.35
CXCR2 P25025 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL27998012 0.88 TSHR (0.42) ALDH1A1LMNATSHRKMT2A
Methanesulfonic Acid Ethyl Ester SCHEMBL27999978 0.80 PSIP1 (0.39) ALDH1A1LMNASMN1; SMN2PTGS2TSHR
Methanesulfonic Acid Ethyl Ester SCHEMBL27623177 0.78 TSHR (0.44) ALDH1A1LMNASMN1; SMN2PTGS2TSHR
SCHEMBL4940352 0.78 IDO1 (0.55) ALDH1A1PNMTIDO1MAPTMEN1
Methanesulfonic Acid Ethyl Ester SCHEMBL27450293 0.76 CA1 (0.46) ALDH1A1LMNATSHR
SCHEMBL9830432 0.75 TAAR1 (0.49) ALDH1A1LMNAMCOLN3PNMTIDO1
Ether SCHEMBL28856080 0.74 KDM4E (0.47) ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1
SCHEMBL31373399 0.74 RECQL (0.42) ALDH1A1LMNASMN1; SMN2RECQLKMT2A
Methanesulfonic Acid Ethyl Ester SCHEMBL27534530 0.74 USP2 (0.43) ALDH1A1LMNATSHR
Methanesulfonic Acid Ethyl Ester SCHEMBL5533648 0.73 CA1 (0.53) ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566309-A Method for synthesizing Luliconazole HUNAN TRADITIONAL CHINESE MEDICAL COLLEGE 2016-05-11 CN disclosed