Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170691 | 0.86 | PLA2G4A (0.39) | PLA2G4AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12548427 | 0.78 | HSD17B10 (0.54) | PLA2G4AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12548631 | 0.73 | KMT2A (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6840495 | 0.73 | HSD17B10 (0.43) | PLA2G4AKMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9891669 | 0.72 | — | — | |
| SCHEMBL21722413 | 0.72 | PLA2G4A (0.41) | PLA2G4AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31596034 | 0.72 | PLA2G4A (0.41) | PLA2G4AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2877357 | 0.70 | PLA2G4A (0.43) | PLA2G4AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12548426 | 0.70 | PLA2G4A (0.67) | PLA2G4AALDH1A1KDM4E | |
| SCHEMBL22222462 | 0.70 | KCNH2 (0.44) | PLA2G4AKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |