Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860003 | 0.90 | KDM1A (0.57) | RAB9AALDH1A1NPC1HPGDMAPT | |
| Formic Acid SCHEMBL28311850 | 0.83 | GAA (0.51) | RAB9AALDH1A1NPC1HPGDMAPT | |
| Anthranilic Acid SCHEMBL28537840 | 0.81 | KDM4E (0.50) | RAB9AALDH1A1NPC1HPGDMAPT | |
| Benzoic Acid SCHEMBL28455231 | 0.80 | ALDH1A1 (0.72) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL6905573 | 0.79 | KDM1A (0.50) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL8619629 | 0.78 | MAPK1 (0.60) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL17444748 | 0.77 | PARP14 (0.63) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL13416408 | 0.77 | KDM1A (0.68) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL29721986 | 0.76 | MAPK1 (0.69) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL5536448 | 0.76 | MAPK1 (0.69) | RAB9AALDH1A1NPC1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118178238-A | Smearing type mask and preparation method thereof | 美贝斯特(广东)生物科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116999381-A | Soothing and moisturizing essence and preparation method thereof | 广州睿锶汀化妆品制造有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-115245477-A | After-sun repair compound, preparation method and application thereof | 广州市索柔生物科技有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-113318056-A | New-born beautifying, firming and wrinkle-removing composition, preparation method thereof and firming and wrinkle-removing cream | 广州伊尔美生物科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-112315830-A | Plant itching-relieving gel and preparation method thereof | 无锡戴可思生物科技有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-110237011-A | A kind of anti-aging skin care product and preparation method thereof | 菏泽龙池生物科技有限公司 | 2019-09-17 | — | — | CN | claimed |
| CN-108354856-A | A kind of snake oil anti-apolexis composition and its application in cosmetics | 佛山市芊茹化妆品有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-107811912-A | A kind of nourishing breast of quick maintenance and preparation method thereof | 广州柚子舍生物科技有限公司 | 2018-03-20 | — | — | CN | claimed |
| CN-105640868-A | Pearl amino acid stayup brightening and moistening mask and preparation method thereof | 海南京润珍珠生物技术股份有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-119745735-A | Composition with moisturizing and repairing effects and preparation method and application thereof | 广州环亚化妆品科技股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-118267317-A | Soothing preparation capable of remarkably reducing skin surface temperature and preparation method thereof | 博汇美萃生物工程技术(广东)有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118178238-A | Smearing type mask and preparation method thereof | 美贝斯特(广东)生物科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116999381-A | Soothing and moisturizing essence and preparation method thereof | 广州睿锶汀化妆品制造有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116634990-A | Compositions comprising one or more (bio) -alkanediols with active ingredients | 西姆莱斯股份公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-108553325-A | A kind of eye cream containing diamond alkene | 安婕妤化妆品科技股份有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-107714531-A | Anti-allergy relieving composition and application thereof | 湖南御家化妆品制造有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-107569674-A | Anti-allergy relieving composition and application thereof | 湖南御家化妆品制造有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106619327-A | Anti-allergic facial mask | 佛山市芊茹化妆品有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105769663-A | Moisture preservation cleansing water with easing and calming functions and method for preparing moisture preservation cleansing water | 广州丹奇日用化工厂有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105640868-A | Pearl amino acid stayup brightening and moistening mask and preparation method thereof | 海南京润珍珠生物技术股份有限公司 | 2016-06-08 | — | — | CN | disclosed |