Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 10/20 | 0.40 |
| ▸ | CA1 | P00915 | 9/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 7/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28272444 | 1.00 | CYP3A4 (0.46) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL16759507 | 1.00 | CYP3A4 (0.46) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL28142509 | 0.98 | CYP3A4 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL1710462 | 0.92 | CYP3A4 (0.53) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL1710465 | 0.92 | CYP3A4 (0.53) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL8982625 | 0.92 | CA1 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL12955914 | 0.92 | CA1 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL1962748 | 0.92 | CA1 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL31272586 | 0.92 | CA1 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL16415818 | 0.91 | CA2 (0.46) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203202-A | Quinoxaline derivative and use thereof | 黑钻治疗公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-105566324-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-107001371-B | Oxipurinol class compound and its application | 广东众生睿创生物科技有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-108348525-A | The medical usage of oxipurinol class compound | 广东众生药业股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108349975-A | 4H-pyrazolo [1,5- α ] benzimidazole compound crystal form and preparation method and intermediate thereof | 广东众生药业股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107001371-A | Oxipurinol class compound and its application | 广东众生药业股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |