Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701556 | 0.82 | NR4A2 (0.64) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL31607540 | 0.82 | NR4A2 (0.64) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL3222576 | 0.81 | NR4A2 (0.50) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL11218801 | 0.81 | NR4A2 (0.50) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL28280848 | 0.81 | NR4A2 (0.50) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL27988729 | 0.80 | NR4A1 (0.46) | NR4A2ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL15999018 | 0.79 | NR4A2 (0.52) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL15558170 | 0.79 | NR4A2 (0.69) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7507425 | 0.78 | NR4A2 (0.48) | NR4A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL13824516 | 0.78 | NR4A2 (0.67) | NR4A2KMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593211-A | Indol and indazol derivatives | HOFFMANN LA ROCHE | 2016-05-18 | — | — | CN | disclosed |