SCHEMBL31607540

SCHEMBL31607540

COC(=O)c1cccc2c1ccn2C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 4/20 0.64
TUBB4A P04350 1/20 0.57
TUBB P07437 1/20 0.57
TUBA3C P0DPH7 1/20 0.57
TUBA1B P68363 1/20 0.57
TUBA4A P68366 1/20 0.57
TUBB4B P68371 1/20 0.57
TUBB3 Q13509 1/20 0.57
TUBB2A Q13885 1/20 0.57
TUBB8 Q3ZCM7 1/20 0.57
TUBA3E Q6PEY2 1/20 0.57
TUBA1A Q71U36 1/20 0.57
TUBA1C Q9BQE3 1/20 0.57
TUBB6 Q9BUF5 1/20 0.57
TUBB2B Q9BVA1 1/20 0.57
TUBB1 Q9H4B7 1/20 0.57
MAPT P10636 2/20 0.49
KMT2A Q03164 4/20 0.49
MEN1 O00255 1/20 0.49
KDM4E B2RXH2 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL701556 1.00 NR4A2 (0.64) NR4A2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL28265649 0.85 TUBB4A (0.52) NR4A2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4990737 0.84 TUBB4A (0.54) NR4A2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL3222576 0.82 NR4A2 (0.50) NR4A2MAPTKMT2AMEN1KDM4E
SCHEMBL28280848 0.82 NR4A2 (0.50) NR4A2MAPTKMT2AMEN1KDM4E
SCHEMBL28069774 0.82 NR4A2 (0.50) NR4A2MAPTKMT2AMEN1KDM4E
SCHEMBL11218801 0.82 NR4A2 (0.50) NR4A2MAPTKMT2AMEN1KDM4E
SCHEMBL3923460 0.81 TUBB4A (0.54) NR4A2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1130987 0.81 PTPN1 (0.61) NR4A2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30251521 0.81 PTPN1 (0.61) NR4A2TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120091815-A T-type voltage-gated calcium channel enhancer 广泛研究所股份有限公司 2025-06-03 CN disclosed