Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471738 | 0.91 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL923407 | 0.88 | MEN1 (0.64) | ALDH1A1MEN1KMT2ATSHRKDM1A | |
| Trifluoroacetic Acid SCHEMBL5033621 | 0.87 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL5561161 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL1357212 | 0.85 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL14885856 | 0.84 | POLB (0.58) | ALDH1A1SMN1; SMN2KMT2AKDM1AMAOA | |
| SCHEMBL5561106 | 0.83 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL19570383 | 0.82 | TSHR (0.59) | ALDH1A1MEN1KMT2ATSHRKDM1A | |
| SCHEMBL23050856 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL8690941 | 0.82 | ALDH1A1 (0.76) | ALDH1A1TSHRKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016977-B | A kind of replacement thiadiazine diketone derivative and preparation method thereof and application | 山东大学 | 2016-06-22 | — | — | CN | disclosed |
| CN-105593226-A | Urea compounds and their use as FAAH enzyme inhibitors | BIAL-PORTELA & CA S A | 2016-05-18 | — | — | CN | disclosed |
| CN-104016977-A | Substituted thiadiazine diketone derivative as well as preparation method and application thereof | UNIV SHANDONG | 2014-09-03 | — | — | CN | disclosed |