Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847083 | 0.89 | PIN1 (0.52) | PIN1DRD4DRD2DRD3MEN1 | |
| SCHEMBL20478665 | 0.89 | PIN1 (0.52) | PIN1DRD4DRD2DRD3MEN1 | |
| SCHEMBL20478637 | 0.88 | PIN1 (0.51) | PIN1DRD4DRD2DRD3MEN1 | |
| SCHEMBL12662601 | 0.80 | CA1 (0.53) | PIN1DRD4CA1CA2TAS1R3 | |
| SCHEMBL9325738 | 0.80 | CA1 (0.53) | DRD4CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL1844443 | 0.80 | CA1 (0.53) | DRD4CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL5848209 | 0.79 | CA1 (0.55) | DRD4CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL20478894 | 0.79 | CA1 (0.52) | PIN1DRD4CA1CA2TAS1R3 | |
| SCHEMBL5848210 | 0.79 | CA1 (0.55) | DRD4CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL5520518 | 0.79 | CA1 (0.55) | PIN1DRD4CA1CA2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372550-A | Aryl ether and application thereof | 佩洛通治疗公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105530923-B | Aryl ethers and their use | 佩洛通治疗公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-105530923-A | Aryl ethers and their use | PELOTON THERAPEUTICS INC | 2016-04-27 | — | — | CN | disclosed |