Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251489 | 0.81 | HPGD (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14938606 | 0.75 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1705503 | 0.74 | TSHR (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL160785 | 0.74 | — | — | |
| SCHEMBL3164650 | 0.74 | — | — | |
| SCHEMBL7003465 | 0.72 | TSHR (0.62) | — | |
| SCHEMBL3601874 | 0.71 | — | — | |
| SCHEMBL3603367 | 0.71 | TAAR1 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17134206 | 0.71 | — | — | |
| SCHEMBL3616684 | 0.71 | TAAR1 (0.33) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555766-A | Aminomethyl-biaryl derivatives as complement factor D inhibitors and uses thereof | NOVARTIS AG | 2016-05-04 | — | — | CN | disclosed |