Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492552 | 0.93 | MAPT (0.78) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL866785 | 0.93 | MAPT (0.78) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4905569 | 0.92 | MAPT (0.76) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL3529060 | 0.85 | MAPT (0.82) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL13964419 | 0.84 | MAPT (0.66) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28803930 | 0.84 | MAPT (0.52) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL11112523 | 0.84 | NPSR1 (0.60) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7292289 | 0.83 | RAB9A (0.67) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28440005 | 0.83 | HDAC1 (0.56) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL25392583 | 0.83 | MAPT (0.72) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283641-A | Preparation method and application of high-purity N, N' -bis- (4-amino-2-chlorophenyl) -terephthalamide | 常州市阳光药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-105646267-A | Aromatic diamine monomer and preparation method thereof | 东华大学 | 2016-06-08 | — | — | CN | claimed |
| CN-116283641-A | Preparation method and application of high-purity N, N' -bis- (4-amino-2-chlorophenyl) -terephthalamide | 常州市阳光药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283641-A | Preparation method and application of high-purity N, N' -bis- (4-amino-2-chlorophenyl) -terephthalamide | 常州市阳光药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-105646267-A | Aromatic diamine monomer and preparation method thereof | 东华大学 | 2016-06-08 | — | — | CN | disclosed |