Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28070320

N.O=C(O)Nn1ccnc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.38
TSHR P16473 1/20 0.36
TBXAS1 P24557 6/20 0.34
ADH5 P11766 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.32
NFKB1 P19838 1/20 0.31
QPCT Q16769 1/20 0.31
HSD17B10 Q99714 1/20 0.31
QPCTL Q9NXS2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170781 0.98
SCHEMBL11067549 0.82 ALDH1A1 (0.39) ALDH1A1EGLN3TSHRTBXAS1HTT
SCHEMBL9113432 0.80
SCHEMBL1906544 0.78
SCHEMBL28172332 0.78
SCHEMBL27435422 0.78
Hydrochloric Acid SCHEMBL28307730 0.77 CYP3A4 (0.37) ALDH1A1EGLN3TBXAS1HTTNFKB1
SCHEMBL27427200 0.77 HTT (0.41) ALDH1A1EGLN3TSHRTDP1HTT
SCHEMBL28704185 0.76
SCHEMBL29156130 0.75 MAPT (0.36) ALDH1A1EGLN3TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105738612-A Cell detection methods and reagents having a releasable labelling moiety 美天施生物科技有限责任公司 2016-07-06 CN disclosed