Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070382 | 0.90 | TTK (0.45) | MAPK10ALK | |
| SCHEMBL28382399 | 0.90 | CHEK1 (0.40) | CHEK1 | |
| SCHEMBL28070380 | 0.90 | TTK (0.41) | — | |
| SCHEMBL28070403 | 0.87 | — | — | |
| SCHEMBL28070401 | 0.87 | ALK (0.40) | ALK | |
| SCHEMBL28296963 | 0.86 | CHEK1 (0.37) | CHEK1KCNH2 | |
| SCHEMBL28384435 | 0.85 | — | — | |
| SCHEMBL28388175 | 0.85 | MAP4K1 (0.43) | — | |
| SCHEMBL28383472 | 0.85 | KIT (0.39) | ALK | |
| SCHEMBL28388107 | 0.84 | FLT3 (0.40) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | claimed |
| CN-105682661-A | Certain chemical entities, compositions, and methods | 润新生物公司 | 2016-06-15 | — | — | CN | claimed |
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | disclosed |
| CN-105682661-A | Certain chemical entities, compositions, and methods | 润新生物公司 | 2016-06-15 | — | — | CN | disclosed |