Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 9/20 | 0.46 |
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070907 | 1.00 | ACE (0.53) | ACEITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL21639310 | 0.86 | ACE (0.59) | ACEITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL21639309 | 0.86 | ACE (0.59) | ACEITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL15432845 | 0.85 | GRB2 (0.52) | ACEITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL18918277 | 0.85 | GRB2 (0.52) | ACEITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL28921935 | 0.85 | GRB2 (0.52) | ACEITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL28070927 | 0.84 | ATM (0.42) | ACE | |
| SCHEMBL28070926 | 0.84 | ATM (0.42) | ACE | |
| SCHEMBL16972916 | 0.84 | ACE (0.57) | ACEITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL16972918 | 0.84 | ACE (0.57) | ACEITGB3ITGA2BITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912683-A | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-105641707-A | Conjugates of cytotoxic molecules and cell-binding receptor molecules | 杭州多禧生物科技有限公司 | 2016-06-08 | — | — | CN | disclosed |