Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 7/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070927 | 1.00 | ATM (0.42) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL28921915 | 0.86 | GRB2 (0.46) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL18918288 | 0.86 | GRB2 (0.46) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL18928697 | 0.85 | ATM (0.45) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL22044541 | 0.85 | ATM (0.45) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL22044576 | 0.85 | ATM (0.45) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL19479915 | 0.85 | ATM (0.45) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL28070779 | 0.85 | ATM (0.39) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL28070782 | 0.85 | ATM (0.39) | ATMMMEMMEL1ACEAPP | |
| SCHEMBL28070907 | 0.84 | ACE (0.53) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110279872-A | Conjugated body of the cytotoxic molecule with cell bound receptor molecule | 杭州多禧生物科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-109912683-A | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-105641707-A | Conjugates of cytotoxic molecules and cell-binding receptor molecules | 杭州多禧生物科技有限公司 | 2016-06-08 | — | — | CN | disclosed |