Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 7/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 5/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070782 | 1.00 | ATM (0.39) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL28302636 | 0.89 | PPARG (0.37) | ATMPPARGPPARABCL2MCL1 | |
| SCHEMBL18918272 | 0.87 | ALDH1A1 (0.41) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL19473311 | 0.87 | ALDH1A1 (0.41) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL18925550 | 0.87 | ALDH1A1 (0.41) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL28337627 | 0.87 | ATM (0.42) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL29390410 | 0.87 | ATM (0.42) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL18918287 | 0.87 | ATM (0.42) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL18918286 | 0.87 | ATM (0.42) | ATMPPARGPPARAMMEMMEL1 | |
| SCHEMBL28070908 | 0.85 | ACE (0.49) | PPARGPPARAACEBCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110279872-A | Conjugated body of the cytotoxic molecule with cell bound receptor molecule | 杭州多禧生物科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-109912683-A | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-105641707-A | Conjugates of cytotoxic molecules and cell-binding receptor molecules | 杭州多禧生物科技有限公司 | 2016-06-08 | — | — | CN | disclosed |