Hexane

Hexane

SCHEMBL28070939

CCCCCC.CN=C=O.CN=C=O

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.60
CASP1 P29466 1/20 0.60
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.38
CES2 O00748 4/20 0.36
CES1 P23141 4/20 0.36
NAAA Q02083 1/20 0.36
SLC22A1 O15245 2/20 0.35
SLC22A2 O15244 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
EPHX2 P34913 1/20 0.35
AKR1B1 P15121 1/20 0.35
ALDH1A1 P00352 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL28180405 1.00 TSHR (0.60) TSHRCASP1THRBLMNACES2
Octane SCHEMBL28993765 0.89 TSHR (0.47) TSHRCASP1THRBLMNACES2
SCHEMBL8470522 0.81 TSHR (0.45) TSHRCASP1NAAA
Hexane SCHEMBL10567935 0.78
Hexane SCHEMBL29173170 0.78 TSHR (0.41) TSHRTHRBLMNACES2CES1
SCHEMBL2765 0.78
SCHEMBL28124906 0.78
Hexane SCHEMBL3357674 0.75 TSHR (0.39) TSHRTHRBLMNACES2CES1
Hexane SCHEMBL6756710 0.75 TSHR (0.39) TSHRTHRBLMNACES2CES1
Hexane SCHEMBL10390111 0.75 NAAA (0.44) TSHRTHRBLMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110270065-A Golf with sandwich layer outside foaming inner core and thermosetting property 阿库施耐特公司 2019-09-24 CN disclosed
CN-105646817-B Polycarbonate diol, process for producing the same, and polyurethane and active energy ray-curable polymer composition each comprising the same 三菱化学株式会社 2019-08-13 CN disclosed
CN-104689530-B The multi-layer golf ball of foamed core with optional distribution of weight 阿库施耐特公司 2017-12-15 CN disclosed
CN-105646817-A Polycarbonate diol, process for producing the same, and polyurethane and active energy ray-curable polymer composition each comprising the same 三菱化学株式会社 2016-06-08 CN disclosed