Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.50 |
| ▸ | KDM5C | P41229 | 2/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22712368 | 0.89 | GRM5 (0.48) | GPR119KDM5CKDM2AKDM3AGRM5 | |
| SCHEMBL31260529 | 0.89 | PIK3CA (0.47) | GPR119KDM5CKDM2AKDM3ASRC | |
| SCHEMBL1781995 | 0.83 | USP30 (0.53) | GPR119USP30KDM4EPKMEGFR | |
| SCHEMBL2225927 | 0.81 | KDM5C (0.44) | GPR119KDM5CKDM2AKDM3AKDM6B | |
| SCHEMBL14692527 | 0.81 | GPR119 (0.46) | GPR119KDM5CKDM2AKDM3AKDM4E | |
| SCHEMBL22730550 | 0.81 | DDB1 (0.48) | GPR119KDM5CKDM2AKDM3AKDM4E | |
| SCHEMBL18376153 | 0.81 | GPR119 (0.47) | GPR119KDM5CKDM2AKDM3AKDM4E | |
| SCHEMBL1653749 | 0.81 | TNK2 (0.56) | GPR119USP30EGFRSRCHPGDS | |
| SCHEMBL18367623 | 0.80 | GPR119 (0.46) | GPR119KDM4EPKM | |
| SCHEMBL16716871 | 0.80 | GPR119 (0.46) | GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646492-A | Five-membered-aromatic-heterocycte-containing substituted xanthine compound and preparation method and use thereof | 中国医学科学院药物研究所 | 2016-06-08 | — | — | CN | disclosed |