Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17766340 | 0.98 | EP300 (0.44) | EP300EPHX2FAAHPPARAGMNN | |
| SCHEMBL10490328 | 0.98 | EP300 (0.41) | EP300EPHX2FAAHPPARA | |
| SCHEMBL512965 | 0.87 | CYP2D6 (0.32) | CYP2C19 | |
| SCHEMBL512962 | 0.87 | CYP2D6 (0.32) | CYP2C19 | |
| SCHEMBL8477683 | 0.86 | EP300 (0.42) | EP300FAAHGMNNUSP2LMNA | |
| SCHEMBL4242173 | 0.86 | CYP2D6 (0.31) | CYP2C19 | |
| SCHEMBL16053743 | 0.86 | CYP2D6 (0.31) | CYP2C19 | |
| SCHEMBL9262531 | 0.80 | EP300 (0.41) | EP300EPHX2FAAHPPARA | |
| SCHEMBL514123 | 0.80 | — | — | |
| SCHEMBL514120 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321610-B | Ceclozapine sulfate and preparation method and application thereof | 湖南润星制药有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-112321610-A | Ceclozapine sulfate and preparation method and application thereof | 湖南润星制药有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-105646543-B | A kind of Cefquinome crystal and preparation method thereof | 天津大学 | 2018-03-27 | — | — | CN | disclosed |
| CN-105646543-A | Cefquinome crystal and preparation method thereof | 天津大学 | 2016-06-08 | — | — | CN | disclosed |