SCHEMBL8477683

SCHEMBL8477683

CCCCCC=C(C)C(=O)OS(C)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.42
FAAH O00519 3/20 0.35
TERT O14746 2/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX15 P16050 1/20 0.33
APEX1 P27695 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
DUSP3 P51452 1/20 0.33
MMP2 P08253 1/20 0.33
FABP4 P15090 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28070969 0.86 EP300 (0.42) EP300FAAHGMNNUSP2LMNA
SCHEMBL17766340 0.85 EP300 (0.44) EP300FAAHTERTGMNNUSP2
SCHEMBL10490328 0.85 EP300 (0.41) EP300FAAHCCR2
SCHEMBL28565576 0.80
SCHEMBL9242927 0.78 EP300 (0.52) EP300FAAHTERTGMNNUSP2
SCHEMBL1642982 0.78 EP300 (0.47) EP300FAAHTERTGMNNUSP2
SCHEMBL4919155 0.78 EP300 (0.47) EP300FAAHGMNNUSP2LMNA
SCHEMBL14890135 0.78 EP300 (0.52) EP300FAAHTERTGMNNUSP2
SCHEMBL3433546 0.78 EP300 (0.52) EP300FAAHTERTGMNNUSP2
SCHEMBL5459895 0.78 EP300 (0.47) EP300FAAHTERTGMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5935950-A AN ANTIBIOTIC COMPRISING A PYRIDINIUM RING WHICH CAN HYDROLYZABLE IN VIVO HOFFMANN-LA ROCHE INC. (US) 1999-08-10 US disclosed
CN-1184815-A Cephalosporin pyridinium derinvatives HOFFMANN LA ROCHE (CH) 1998-06-17 CN disclosed