Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48946 | 0.96 | — | — | |
| Hydrazine SCHEMBL17761197 | 0.94 | — | — | |
| Pyridine SCHEMBL28222764 | 0.81 | — | — | |
| SCHEMBL27772678 | 0.81 | — | — | |
| SCHEMBL28109829 | 0.80 | TAAR1 (0.36) | — | |
| Piperazine SCHEMBL28348866 | 0.77 | CXCR4 (0.33) | CXCR4 | |
| SCHEMBL27791981 | 0.77 | TAAR1 (0.37) | — | |
| SCHEMBL8059540 | 0.76 | TAAR1 (0.33) | — | |
| Piperazine SCHEMBL28228877 | 0.76 | TAAR1 (0.33) | — | |
| SCHEMBL3260061 | 0.76 | GNAO1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105556392-B | Stripper composition for removing photoresist and method for stripping photoresist using the same | 株式会社LG化学 | 2019-09-06 | — | — | CN | claimed |
| CN-107722293-A | A kind of nitrogenous hyperbranched fire retardant and its preparation method and application | 中国人民武装警察部队学院 | 2018-02-23 | — | — | CN | claimed |
| CN-104177894-B | Corrosion protection for the chromate-free of fuel tank | 美凯威奇兄弟有限责任两合公司 | 2018-01-02 | — | — | CN | claimed |
| CN-106977697-A | Liquid infiltration technique Latent epoxy resin for preparing fibre reinforced composites | 赢创德固赛有限公司 | 2017-07-25 | — | — | CN | claimed |
| CN-106947061-A | Liquid infiltration technique Latent epoxy resin for preparing fibrous composite | 赢创德固赛有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-106573868-A | Neutralization of acidic catalysts in production of phenol | 陶氏环球技术有限责任公司 | 2017-04-19 | — | — | CN | claimed |
| CN-105814108-A | Process for forming an organic polymer in a reaction of a polyene, an epoxy resin and a mixture of thiol and amine curing agents | 陶氏环球技术有限责任公司 | 2016-07-27 | — | — | CN | claimed |
| CN-109415609-A | Adhesive composite and adhesive sheet | 株式会社寺冈制作所 | 2019-03-01 | — | — | CN | disclosed |
| CN-106459379-B | Curing agent composition | 陶氏环球技术有限责任公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-105555875-B | Crosslinked composition and forming method thereof | 美国陶氏有机硅公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-105531301-B | Crosslinked compositions and methods of forming the same | 道康宁公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107743501-A | Thermosetting epoxy resin composition for the preparation of outdoor articles and articles obtained therefrom | 亨斯迈先进材料特许（瑞士）有限公司 | 2018-02-27 | — | — | CN | disclosed |
| CN-106977697-A | Liquid infiltration technique Latent epoxy resin for preparing fibre reinforced composites | 赢创德固赛有限公司 | 2017-07-25 | — | — | CN | disclosed |
| CN-106947061-A | Liquid infiltration technique Latent epoxy resin for preparing fibrous composite | 赢创德固赛有限公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-106459379-A | Curing agent composition | 陶氏环球技术有限责任公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105849189-A | Polyester-based resin composition, and molded body using the resin composition | 三菱瓦斯化学株式会社 | 2016-08-10 | — | — | CN | disclosed |