Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527080 | 0.94 | TDP1 (0.50) | TDP1HSD17B10TSHRLMNA | |
| Glycerin SCHEMBL28087126 | 0.91 | TDP1 (0.44) | TDP1HSD17B10TSHRLMNA | |
| Butane SCHEMBL2317610 | 0.87 | TDP1 (0.59) | TDP1HSD17B10TSHR | |
| Propylene Glycol SCHEMBL17272919 | 0.87 | TDP1 (0.52) | TDP1HSD17B10TSHRLMNA | |
| Propylene Glycol SCHEMBL320813 | 0.87 | TDP1 (0.52) | TDP1HSD17B10TSHRLMNA | |
| SCHEMBL2270646 | 0.86 | TDP1 (0.50) | TDP1HSD17B10TSHRLMNA | |
| Propanol SCHEMBL28164233 | 0.85 | TDP1 (0.57) | TDP1HSD17B10TSHR | |
| Alcohol SCHEMBL16163804 | 0.85 | TDP1 (0.55) | TDP1HSD17B10TSHR | |
| SCHEMBL3193159 | 0.84 | TDP1 (0.54) | TDP1HSD17B10TSHRLMNA | |
| SCHEMBL18322329 | 0.84 | TDP1 (0.54) | TDP1HSD17B10TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103109391-B | Nanowire-polymer composite electrode | 加利福尼亚大学董事会 | 2016-07-20 | — | — | CN | disclosed |