Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | STAMBP | O95630 | 1/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985376 | 0.80 | MAPK1 (0.41) | PSMD14LMNAKDM4EL3MBTL1CYP11B2 | |
| SCHEMBL17675123 | 0.74 | NNMT (0.49) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL27985375 | 0.71 | GLA (0.40) | LMNAKDM4E | |
| SCHEMBL24233687 | 0.70 | — | — | |
| SCHEMBL16495711 | 0.70 | NNMT (0.56) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL5672576 | 0.70 | KDM1A (0.45) | KDM4E | |
| SCHEMBL30445575 | 0.70 | NNMT (0.51) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL16112727 | 0.70 | NNMT (0.38) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL17675163 | 0.68 | NNMT (0.58) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL26607684 | 0.68 | NNMT (0.58) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814040-A | Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1 | 癌症研究科技有限公司 | 2016-07-27 | — | — | CN | disclosed |