O-Xylene — predicted protein targets

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	4/20	0.67

▸	ACHE	P22303	3/20	0.67

▸	ALDH1A1	P00352	4/20	0.43

▸	CA1	P00915	2/20	0.43

▸	CA2	P00918	2/20	0.43

▸	CA7	P43166	2/20	0.43

▸	CA9	Q16790	2/20	0.43

▸	CYP3A4	P08684	1/20	0.41

▸	TDP1	Q9NUW8	1/20	0.41

▸	CYP1A2	P05177	2/20	0.40

▸	CYP2A6	P11509	2/20	0.40

▸	LMNA	P02545	1/20	0.37

▸	ALOX12	P18054	1/20	0.37

▸	MAPT	P10636	1/20	0.36

▸	HTT	P42858	1/20	0.36

▸	ESR1	P03372	1/20	0.36

▸	TAAR1	Q96RJ0	1/20	0.35

▸	HSD17B10	Q99714	1/20	0.35

▸	TRPA1	O75762	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
O-Xylene SCHEMBL9466816	0.87	TSHR (0.67)	TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL28634943	0.86	TSHR (0.77)	TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL6933035	0.82	TSHR (0.83)	TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11035539	0.82	TSHR (1.00)	TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL8216257	0.82	TSHR (1.00)	TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29385454	0.82	—	—
O-Xylene SCHEMBL2854068	0.82	—	—
O-Xylene SCHEMBL11034038	0.82	TSHR (1.00)	TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL10522915	0.82	TSHR (1.00)	TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL170581	0.82	TSHR (1.00)	TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-105683203-A	VINYLSILANES FOR USE IN FUNCTIONALIZED ELASTOMERIC POLYMERS	盛禧奥欧洲有限责任公司	2016-06-15	—	—	CN	disclosed