Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30506468 | 0.89 | DEGS1 (0.48) | GSK3BDYRK1AMAPK1DEGS1NAMPT | |
| SCHEMBL22606745 | 0.89 | DEGS1 (0.48) | GSK3BDYRK1AMAPK1DEGS1NAMPT | |
| SCHEMBL31726922 | 0.87 | MAPK1 (0.43) | GSK3BDYRK1AMAPK1DEGS1NAMPT | |
| SCHEMBL16296314 | 0.86 | GSK3B (0.41) | GSK3BDYRK1AMAPK1DEGS1NAMPT | |
| SCHEMBL24738966 | 0.86 | GSK3B (0.43) | GSK3BDYRK1AMAPK1DEGS1NAMPT | |
| SCHEMBL27946209 | 0.85 | MAPK1 (0.42) | GSK3BDYRK1AMAPK1DEGS1NAMPT | |
| SCHEMBL31727221 | 0.81 | NAMPT (0.41) | GSK3BDYRK1AMAPK1DEGS1NAMPT | |
| SCHEMBL24738932 | 0.80 | GAA (0.45) | GSK3BDYRK1ADEGS1NAMPTGRIN2B | |
| SCHEMBL2307440 | 0.80 | GSK3B (0.44) | GSK3BDYRK1ADEGS1NAMPTGRIN2B | |
| SCHEMBL23107411 | 0.79 | NAMPT (0.48) | GSK3BDYRK1AMAPK1NAMPTGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459382-B | For suppressing the heterocyclic compound of PASK | 拜奥埃内杰尼克斯公司 | 2016-06-29 | — | — | CN | disclosed |