SCHEMBL28071561

SCHEMBL28071561

O=C(SC(=O)c1ccccc1O)c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.58
HPGD P15428 7/20 0.58
ALDH1A1 P00352 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
CA1 P00915 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 2/20 0.58
CA2 P00918 2/20 0.58
CA4 P22748 2/20 0.58
CA14 Q9ULX7 2/20 0.58
HMGB1 P09429 1/20 0.58
CA6 P23280 1/20 0.58
CA7 P43166 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
HSD17B10 Q99714 4/20 0.56
MAPT P10636 4/20 0.56
TSHR P16473 2/20 0.56
GAA P10253 2/20 0.52
HIF1A Q16665 2/20 0.52
MPO P05164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1585224 0.87 KDM4E (0.50) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL10397162 0.82 KDM4E (0.50) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL212174 0.81 HPGD (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL10398061 0.79 KDM4E (0.61) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL3074700 0.78 HPGD (0.56) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL2964435 0.76 KDM4E (0.48) KDM4EHPGDALDH1A1SMN1; SMN2CA1
2,2'-Dihydroxybenzphenone SCHEMBL29572496 0.76 HPGD (0.67) KDM4EHPGDALDH1A1SMN1; SMN2CA1
2,2'-Dihydroxybenzphenone SCHEMBL18422 0.76 HPGD (0.67) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL29861559 0.76 KDM4E (0.67) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL9797513 0.76 KDM4E (0.67) KDM4EHPGDALDH1A1SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102803262-B Novel hindered amine light stabilizers 巴斯夫欧洲公司 2016-08-03 CN disclosed
CN-104262678-B Additive for polymer HUANG XIURU (CN) 2016-06-01 CN disclosed