Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307730 | 0.98 | KDM4E (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| SCHEMBL5404182 | 0.96 | KDM4E (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| SCHEMBL29742701 | 0.87 | TSHR (0.45) | ALDH1A1HPGDTSHRHSD17B10HTT | |
| SCHEMBL777209 | 0.80 | KMT2A (0.46) | ALDH1A1HPGDSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL10174588 | 0.80 | CLCN2 (0.41) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL9770270 | 0.79 | NAAA (0.55) | ALDH1A1TSHRLMNAMAPTHTT | |
| SCHEMBL59254 | 0.79 | NAAA (0.55) | ALDH1A1TSHRLMNAMAPTHTT | |
| SCHEMBL9770247 | 0.79 | NAAA (0.55) | ALDH1A1TSHRLMNAMAPTHTT | |
| SCHEMBL3082597 | 0.78 | HDAC8 (0.50) | ALDH1A1CA1CA9CA12CA2 | |
| SCHEMBL27590172 | 0.78 | CES2 (0.52) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946028-B | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-09-24 | — | — | CN | claimed |
| CN-117946028-A | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946028-B | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-117946028-A | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-04-30 | — | — | CN | disclosed |
| US-11584773-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| EP-3943500-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | Agilent Technologies, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| US-20220002334-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2022-01-06 | — | — | US | disclosed |
| EP-3137478-B1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | AGILENT TECHNOLOGIES INC (US) | 2021-09-22 | — | — | EP | disclosed |
| CN-106255697-B | Phosphorus protecting group and preparation method and application thereof | 安捷伦科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| US-20190194242-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2019-06-27 | — | — | US | disclosed |
| US-10196418-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| EP-1246625-A2 | METHODS AND COMPOSITIONS FOR MITIGATING PAIN USING NITRATE ESTERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049275-A2 | METHODS AND COMPOSITIONS FOR MITIGATING PAIN USING NITRATE ESTERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2001-07-12 | — | — | WO | disclosed |
| US-5021491-A | Heat stabilizers for thermoplastic chloropolymers | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194242-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HPGD 2164/4885 |
| US-10196418-B2 | Phosphorous protecting groups and methods of preparation and use thereof | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HPGD 2164/4885 |
| US-20220002334-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HPGD 2164/4885 |
| US-11584773-B2 | Phosphorous protecting groups and methods of preparation and use thereof | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HPGD 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.