Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.47 |
| ▸ | PRKACA | P17612 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | PRKX | P51817 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072056 | 1.00 | ROCK1 (0.47) | ROCK1PRKACAGSK3APRKXCLK4 | |
| SCHEMBL28098601 | 0.85 | RIPK1 (0.49) | ROCK1PRKACAGSK3APRKXCLK4 | |
| SCHEMBL28750811 | 0.85 | RIPK1 (0.49) | ROCK1PRKACAGSK3APRKXCLK4 | |
| SCHEMBL5458502 | 0.84 | AOC3 (0.47) | TACR3ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL5453374 | 0.81 | TACR3 (0.47) | TACR3ALDH1A1NPC1 | |
| SCHEMBL5320174 | 0.81 | TACR3 (0.47) | TACR3ALDH1A1NPC1 | |
| SCHEMBL17956754 | 0.80 | TACR3 (0.46) | TACR3ALDH1A1NPC1 | |
| SCHEMBL11239095 | 0.80 | NPC1 (0.54) | TACR3ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL3886204 | 0.78 | ROCK1 (0.56) | ROCK1PRKACAGSK3APRKXCLK4 | |
| SCHEMBL1120036 | 0.78 | ROCK1 (0.56) | ROCK1PRKACAGSK3APRKXCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106513041-A | (S)-1-(3-hydroxy-1-phenylpropyl)thiourea modified Al-Anderson type heteropolyacid catalyst, preparation method and application thereof | 上海应用技术大学 | 2017-03-22 | — | — | CN | claimed |
| CN-106475141-A | (S) the unilateral Fe Anderson type heteropolyacid catalyst modified of 1 (3 hydroxyl 1 phenylpropyl) thiourea, preparation method and applications | 上海应用技术大学 | 2017-03-08 | — | — | CN | claimed |
| CN-105797770-B | (S) the thiourea modified Cr Anderson types heteropolyacid catalyst of 1 (phenylpropyl of 3 hydroxyl 1), preparation method and applications | 上海应用技术学院 | 2018-03-30 | — | — | CN | disclosed |
| CN-105665019-B | (S) the thiourea modified Mn Anderson types heteropolyacid catalyst of 1 (phenylpropyl of 3 hydroxyl 1), preparation method and applications | 上海应用技术学院 | 2018-03-02 | — | — | CN | disclosed |
| CN-106513041-A | (S)-1-(3-hydroxy-1-phenylpropyl)thiourea modified Al-Anderson type heteropolyacid catalyst, preparation method and application thereof | 上海应用技术大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-106513041-A | (S)-1-(3-hydroxy-1-phenylpropyl)thiourea modified Al-Anderson type heteropolyacid catalyst, preparation method and application thereof | 上海应用技术大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-106513041-A | (S)-1-(3-hydroxy-1-phenylpropyl)thiourea modified Al-Anderson type heteropolyacid catalyst, preparation method and application thereof | 上海应用技术大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-106475141-A | (S) the unilateral Fe Anderson type heteropolyacid catalyst modified of 1 (3 hydroxyl 1 phenylpropyl) thiourea, preparation method and applications | 上海应用技术大学 | 2017-03-08 | — | — | CN | disclosed |
| CN-105797770-A | (S)-1-(3-hydroxyl-1-phenylpropyl) thiourea modified Cr-Anderson type heteropolyacid catalyst as well as preparation method and application thereof | 上海应用技术学院 | 2016-07-27 | — | — | CN | disclosed |
| CN-105797770-A | (S)-1-(3-hydroxyl-1-phenylpropyl) thiourea modified Cr-Anderson type heteropolyacid catalyst as well as preparation method and application thereof | 上海应用技术学院 | 2016-07-27 | — | — | CN | disclosed |
| CN-105797770-A | (S)-1-(3-hydroxyl-1-phenylpropyl) thiourea modified Cr-Anderson type heteropolyacid catalyst as well as preparation method and application thereof | 上海应用技术学院 | 2016-07-27 | — | — | CN | disclosed |
| CN-105665019-A | Mn-Anderson type heteropolyacid catalyst modified with (S)-1-(3-hydroxy-1-phenylpropyl) thiourea, as well as preparation method and application thereof | 上海应用技术学院 | 2016-06-15 | — | — | CN | disclosed |
| CN-105665019-A | Mn-Anderson type heteropolyacid catalyst modified with (S)-1-(3-hydroxy-1-phenylpropyl) thiourea, as well as preparation method and application thereof | 上海应用技术学院 | 2016-06-15 | — | — | CN | disclosed |
| CN-105665019-A | Mn-Anderson type heteropolyacid catalyst modified with (S)-1-(3-hydroxy-1-phenylpropyl) thiourea, as well as preparation method and application thereof | 上海应用技术学院 | 2016-06-15 | — | — | CN | disclosed |