Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 13/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065632 | 0.82 | CCR1 (0.34) | CCR1KCNH2TERTALDH1A1 | |
| SCHEMBL20442093 | 0.81 | F2R (0.41) | CCR1KCNH2TERTALDH1A1F2R | |
| SCHEMBL29600898 | 0.81 | F2R (0.41) | CCR1KCNH2TERTALDH1A1F2R | |
| SCHEMBL12664449 | 0.78 | KCNH2 (0.45) | CCR1KCNH2TERTALDH1A1 | |
| SCHEMBL27600750 | 0.78 | BACE1 (0.39) | KCNH2LMNAKDM4E | |
| SCHEMBL27788777 | 0.78 | KCNH2 (0.36) | KCNH2ALDH1A1LMNA | |
| SCHEMBL28119095 | 0.78 | CYP3A4 (0.38) | KCNH2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5924102 | 0.78 | SMN1; SMN2 (0.41) | CCR1KCNH2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28659624 | 0.78 | KCNH2 (0.40) | KCNH2LMNA | |
| SCHEMBL28298079 | 0.78 | KCNH2 (0.40) | CCR1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793250-A | Heteroaryl derivatives for the treatment of respiratory diseases | 奇斯药制品公司 | 2016-07-20 | — | — | CN | disclosed |