Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917852 | 0.82 | CYP19A1 (0.44) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL8462926 | 0.82 | TDP1 (0.54) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL28424615 | 0.80 | CYP19A1 (0.42) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL3968791 | 0.78 | TSHR (0.48) | TDP1ALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL333015 | 0.78 | ADRA2A (0.50) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL2267201 | 0.78 | CYP19A1 (0.50) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL8469907 | 0.76 | TDP1 (0.49) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL4292777 | 0.76 | CYP19A1 (0.49) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL113763 | 0.76 | CYP19A1 (0.49) | CYP19A1TDP1CA12CA1CA2 | |
| SCHEMBL2375801 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110462049-A | The 2- ketone acid and its C of elongation are prepared by the gene modification to microbial metabolism approach5-C10The method of compound | DOW GLOBAL TECHNOLOGIES LLC | 2019-11-15 | — | — | CN | disclosed |
| CN-109790554-A | The method of the 2- ketone acid and its C5-C10 compound of elongation is prepared by the gene modification to microbial metabolism approach | 陶氏环球技术有限责任公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105793431-A | Processes to prepare elongated 2-ketoacids and c6-c10 compounds therefrom via genetic modifications to microbial metabolic pathways | 陶氏环球技术有限责任公司 | 2016-07-20 | — | — | CN | disclosed |