Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31609254 | 1.00 | SIGMAR1 (0.51) | SIGMAR1MAPTP2RX3DNM1SMN1; SMN2 | |
| SCHEMBL15480483 | 0.98 | SIGMAR1 (0.52) | SIGMAR1MAPTP2RX3DNM1SMN1; SMN2 | |
| SCHEMBL30972545 | 0.95 | SIGMAR1 (0.50) | SIGMAR1MAPTP2RX3DNM1SMN1; SMN2 | |
| SCHEMBL410726 | 0.93 | SIGMAR1 (0.54) | SIGMAR1MAPTP2RX3DNM1SMN1; SMN2 | |
| SCHEMBL30972551 | 0.88 | SIGMAR1 (0.43) | SIGMAR1MAPTP2RX3DNM1SMN1; SMN2 | |
| SCHEMBL30923410 | 0.86 | SIGMAR1 (0.38) | SIGMAR1MAOAMAOBGRIN1GRIN2A | |
| SCHEMBL20045111 | 0.86 | SIGMAR1 (0.38) | SIGMAR1MAOAMAOBGRIN1GRIN2A | |
| SCHEMBL19896374 | 0.86 | SIGMAR1 (0.38) | SIGMAR1MAOAMAOBGRIN1GRIN2A | |
| SCHEMBL20374639 | 0.85 | SIGMAR1 (0.46) | SIGMAR1MAPTP2RX3DNM1SMN1; SMN2 | |
| SCHEMBL9985099 | 0.85 | MAPT (0.53) | SIGMAR1MAPTP2RX3DNM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103951706-B | A kind of small molecule host material based on D-R-A and preparation method thereof, application | 华南理工大学 | 2016-06-22 | — | — | CN | claimed |
| CN-109535397-B | Stable organic light-emitting free radical polymer and OLED (organic light-emitting diode) device based on same | 吉林大学 | 2021-04-27 | — | — | CN | disclosed |
| CN-108610471-B | Photocrosslinkable hole transport polymer and preparation method and application thereof | 华南理工大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-108559484-B | A kind of alkyl bromide is for carbazole derivates room temperature phosphorimetry material and its preparation and application | 太原理工大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-103951706-B | A kind of small molecule host material based on D-R-A and preparation method thereof, application | 华南理工大学 | 2016-06-22 | — | — | CN | disclosed |