SCHEMBL28073136

SCHEMBL28073136

CC(N)(Cc1ccccc1)c1cc[c]cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.53
SLC6A2 P23975 2/20 0.53
CYP2D6 P10635 2/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
CYP1A2 P05177 3/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
CYP3A4 P08684 2/20 0.37
RECQL P46063 1/20 0.37
TRPA1 O75762 1/20 0.37
TACR1 P25103 1/20 0.36
MAPK1 P28482 1/20 0.36
KIF11 P52732 3/20 0.35
PRMT1 Q99873 1/20 0.34
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
HRH1 P35367 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL855070 0.86 TAAR1 (0.64) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL7266792 0.84 TAAR1 (0.61) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
SCHEMBL3033365 0.81 ESR1 (0.47) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
SCHEMBL6555823 0.81 SLC6A2 (0.47) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
SCHEMBL5308339 0.79 SLC6A2 (0.55) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
SCHEMBL5305664 0.78 SLC6A2 (0.55) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
SCHEMBL8865764 0.78 SLC6A2 (0.53) TAAR1SLC6A2LMNASMN1; SMN2HIF1A
SCHEMBL29037325 0.77 TAAR1 (0.52) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL8866021 0.76 SLC6A2 (0.52) TAAR1SLC6A2LMNASMN1; SMN2HIF1A
SCHEMBL8976239 0.76 ESR1 (0.56) TAAR1SLC6A2LMNASMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814015-A Cyclopentadienyl substituted Salan catalysts 埃克森美孚化学专利公司 2016-07-27 CN disclosed