Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178969 | 0.90 | TSHR (0.46) | SLC6A2TAAR1KIF11TSHRCYP1A2 | |
| SCHEMBL855070 | 0.88 | TAAR1 (0.64) | SLC6A2TAAR1KIF11LMNACYP2D6 | |
| Fumaric Acid SCHEMBL8866470 | 0.87 | SLC6A2 (0.47) | SLC6A2TAAR1KIF11LMNASMN1; SMN2 | |
| Maleic Acid SCHEMBL8866450 | 0.87 | SLC6A2 (0.47) | SLC6A2TAAR1KIF11LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7266792 | 0.86 | TAAR1 (0.61) | SLC6A2TAAR1KIF11LMNACYP2D6 | |
| SCHEMBL5305664 | 0.83 | SLC6A2 (0.55) | SLC6A2TAAR1KIF11MEN1KMT2A | |
| SCHEMBL8865764 | 0.83 | SLC6A2 (0.53) | SLC6A2TAAR1KIF11LMNATSHR | |
| Hydrochloric Acid SCHEMBL8866021 | 0.81 | SLC6A2 (0.52) | SLC6A2TAAR1KIF11LMNATSHR | |
| SCHEMBL8976239 | 0.81 | ESR1 (0.56) | SLC6A2TAAR1KIF11MEN1KMT2A | |
| SCHEMBL5305755 | 0.80 | LTA4H (0.52) | SLC6A2TAAR1KIF11HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | claimed |
| US-5539120-A | Arylalkyl-amines having anticonvulsant and neuroprotective properties | AGENCE SPATIALE EUROPEENNE (FR) | 1996-07-23 | — | — | US | claimed |
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | claimed |
| EP-0356035-A2 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1990-02-28 | — | — | EP | claimed |
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |