Tert-Butyl Formate

Tert-Butyl Formate

SCHEMBL28073144

C=CC(N)C1CCNCC1.CC(C)(C)OC=O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butyl Formate SCHEMBL27733520 0.83 TDP1 (0.43) TDP1
SCHEMBL4019377 0.80 DPP4 (0.33)
Tert-Butyl Formate SCHEMBL27731450 0.77 TDP1 (0.52) TDP1
Tert-Butyl Formate SCHEMBL27741789 0.76 TDP1 (0.43) TDP1
Tert-Butyl Formate SCHEMBL27742723 0.76 TDP1 (0.43) TDP1
Tert-Butyl Formate SCHEMBL27962889 0.76 TDP1 (0.46) TDP1
Sulfamide SCHEMBL6017402 0.75 LMNA (0.33)
Tert-Butyl Formate SCHEMBL27722913 0.75 TDP1 (0.50) TDP1
Tert-Butyl Formate SCHEMBL27637918 0.75 TDP1 (0.50) TDP1
Tert-Butyl Formate SCHEMBL28291359 0.75 TDP1 (0.54) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705488-A Acetylcholinesterase inhibitor compounds and 5HT4 serotonergic receptor agonisis, with promnesia effect, methods for the preparation thereof and pharmaceutical compositions containing same 卡昂大学 2016-06-22 CN disclosed