SCHEMBL28073496

SCHEMBL28073496

CCC1C([Zr])=Cc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.39
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
CHRM2 P08172 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD2 P14416 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
NFKB1 P19838 1/20 0.36
CHRM3 P20309 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
THPO P40225 1/20 0.36
OPRK1 P41145 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31345722 0.98 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL813299 0.85 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL812424 0.83 KDM4E (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL812811 0.83 CYP3A4 (0.44) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL812262 0.82 KDM4E (0.45) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6238627 0.78 HTR2A (0.41) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6725256 0.76 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL17008830 0.76 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL4660518 0.76 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL29090062 0.76 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111587256-B Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2023-05-19 CN claimed
CN-110330582-B Making polyolefin products 尤尼威蒂恩技术有限责任公司 2022-04-12 CN claimed
CN-111108130-A Has the advantages ofcontaining-CH2-SiMe3Hybrid catalysts of partially unbridged hafnocenes 埃克森美孚化学专利公司 2020-05-05 CN claimed
CN-105992776-B Manufacture hardness, toughness and the improved polyolefin product of machinability 尤尼威蒂恩技术有限责任公司 2019-05-21 CN claimed
CN-105980424-B Making polyolefin products 尤尼威蒂恩技术有限责任公司 2019-05-21 CN claimed
CN-106029712-B The manufacturing method of polyethylene and its polyethylene 尤尼威蒂恩技术有限责任公司 2019-05-21 CN claimed
CN-108129729-A A kind of preparation process of the novel plastic type magnetron based on permanent-magnet material 宁波市鄞州智伴信息科技有限公司 2018-06-08 CN claimed
CN-106034402-A Making polyolefin products 尤尼威蒂恩技术有限责任公司 2016-10-19 CN claimed
CN-105992776-A Producing polyethylene products with improved stiffness, toughness, and processability 尤尼威蒂恩技术有限责任公司 2016-10-05 CN claimed
CN-111587256-B Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2023-05-19 CN disclosed
CN-112996821-B Mixed catalyst system with condensing agent-adjustable properties 埃克森美孚化学专利公司 2023-04-28 CN disclosed
CN-110330581-B Making polyolefin products 尤尼威蒂恩技术有限责任公司 2022-06-28 CN disclosed
CN-110330582-B Making polyolefin products 尤尼威蒂恩技术有限责任公司 2022-04-12 CN disclosed
CN-105980424-B Making polyolefin products 尤尼威蒂恩技术有限责任公司 2019-05-21 CN disclosed
CN-106029712-B The manufacturing method of polyethylene and its polyethylene 尤尼威蒂恩技术有限责任公司 2019-05-21 CN disclosed
CN-103509060-B Metallocene compound, the carbon monoxide-olefin polymeric comprising metallocene compound and the olefine polymerizing process of use metallocene compound 大林产业株式会社 2016-08-10 CN disclosed