SCHEMBL813299

SCHEMBL813299

CCCC1C([Zr])=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD2 P14416 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
NFKB1 P19838 1/20 0.38
CHRM3 P20309 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38
THPO P40225 1/20 0.38
OPRK1 P41145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL812424 0.98 KDM4E (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL812811 0.91 CYP3A4 (0.44) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL812262 0.89 KDM4E (0.45) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL28073496 0.85 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL31345722 0.83 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7783135 0.79 HTR2A (0.39) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL31672150 0.78 HTR2A (0.41) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL812426 0.76 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
Fluoride Ion SCHEMBL1130903 0.76 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL17023011 0.76 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111587256-B Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2023-05-19 CN claimed
US-11618791-B2 Systems and methods for producing a supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-04-04 US disclosed
CN-114901391-A System and method for producing supported catalysts 埃克森美孚化学专利公司 2022-08-12 CN disclosed
US-20210155723-A1 Systems and Methods for Producing a Supported Catalyst EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-05-27 US disclosed
EP-2872539-B1 INCREASED POLYMER MELT FLOW RATIO VIA FEED OF A SUPPORTED CATALYST SATURATED WITH A SELECTED LIQUID AGENT UNIVATION TECH LLC (US) 2020-12-09 EP disclosed
US-9512254-B2 Increased polymer melt flow ratio via feed of a supported catalyst saturated with a selected liquid agent UNIVATION TECHNOLOGIES, LLC (US) 2016-12-06 US disclosed
EP-1716183-B1 DE-FOAMING SPRAY DRIED CATALYST SLURRIES UNIVATION TECH LLC (US) 2016-04-13 EP disclosed
US-20150133614-A1 Increased Polymer Melt Flow Ratio Via Feed of a Supported Catalyst Saturated With a Selected Liquid Agent UNIVATION TECHNOLOGIES, LLC (US) 2015-05-14 US disclosed
EP-2721078-A1 MULTI-COMPONENT CATALYST SYSTEMS FOR THE PRODUCTION OF REACTOR BLENDS OF POLYPROPYLENE Fina Technology, Inc. (US) 2014-04-23 EP disclosed
US-8633286-B2 Catalyst compositions comprising support materials having an improved particle-size distribution UNIVATION TECHNOLOGIES, LLC (US) 2014-01-21 US disclosed
US-6806328-B2 A HALOGENATED ARYL ALUMINUM PHENOXIDE CATALYST FOR ETHYLENE HOMO- OR COPOLYMERIZATION; MAKING LOW OR HIGH DENSITY POLYMER UNIVATION TECHNOLOGIES, LLC 2004-10-19 US disclosed
US-20040127348-A1 Halogen substituted catalyst system for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2004-07-01 US disclosed
US-6753390-B2 ADDITION POLYMERIZATION; COMBINING HYDROGEN AND ETHYLENE IN SUPPORTED BIMETALLIC CATALYST SYSTEM COMPRISING METALLOCENE IN FLUIDIZED BED UNIVATION TECHNOLOGIES, LLC 2004-06-22 US disclosed
US-20040092387-A1 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC 2004-05-13 US disclosed
US-20040044153-A1 Gas phase polymerization process UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040044154-A1 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040043893-A1 Process for producing fluorinated catalysts UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
WO-2004003037-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC. (US) 2004-01-08 WO disclosed
WO-2004003032-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2004-01-08 WO disclosed
US-20030171514-A1 Polymerization catalyst activator complexes and their use in a polymerization process DOW GLOBAL TECHNOLOGIES LLC 2003-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043893-A1 Process for producing fluorinated catalysts FLI1, AFF1, INF2 HTR2A 3132/4885KDM4E 1585/4885LMNA 2788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.