Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793357 | 0.83 | ASAH1 (0.61) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL10355911 | 0.82 | ASAH1 (0.57) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL3078847 | 0.80 | SMN1; SMN2 (0.59) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL4437431 | 0.80 | ASAH1 (0.62) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL11443588 | 0.80 | KMT2A (0.60) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL250172 | 0.80 | HTT (0.66) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL9791225 | 0.79 | KMT2A (0.60) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL29195649 | 0.79 | ASAH1 (0.62) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL4619935 | 0.79 | ASAH1 (0.64) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL30846011 | 0.79 | ASAH1 (0.62) | ASAH1SMN1; SMN2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103781850-B | Zirconium-containing complex and condensation reaction catalyst, method for preparing the catalyst and composition comprising the catalyst | 道康宁公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-103781823-B | Containing titanium complex and condensation catalyst, prepare the method for this catalyst and comprise the compositions of this catalyst | 道康宁公司 | 2016-08-17 | — | — | CN | disclosed |