Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 13/20 | 0.48 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28073517 | 0.88 | CRACR2A (0.44) | CRACR2AORAI1 | |
| SCHEMBL27904325 | 0.86 | CRACR2A (0.52) | CRACR2AORAI1 | |
| SCHEMBL28073675 | 0.80 | CRACR2A (0.51) | CRACR2AORAI1KCNJ6KCNJ3 | |
| SCHEMBL28099681 | 0.72 | CCR1 (0.36) | — | |
| SCHEMBL27919933 | 0.72 | KDM4E (0.39) | — | |
| SCHEMBL27919939 | 0.70 | PARP1 (0.48) | — | |
| SCHEMBL27919942 | 0.69 | CCR1 (0.36) | — | |
| SCHEMBL1668597 | 0.69 | CRACR2A (0.52) | CRACR2AORAI1 | |
| SCHEMBL27902308 | 0.69 | RIPK2 (0.42) | — | |
| SCHEMBL27902304 | 0.69 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834382-B | The pyrazole derivatives of calcium channel modulators is activated as calcium release | 理森制药股份公司 | 2016-08-03 | — | — | CN | claimed |
| CN-102834382-B | The pyrazole derivatives of calcium channel modulators is activated as calcium release | 理森制药股份公司 | 2016-08-03 | — | — | CN | disclosed |