⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754036 | 1.00 | — | — | |
| SCHEMBL5675955 | 1.00 | — | — | |
| SCHEMBL11742784 | 0.96 | — | — | |
| SCHEMBL16977137 | 0.74 | — | — | |
| SCHEMBL1556924 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL499166 | 0.71 | — | — | |
| SCHEMBL3434947 | 0.71 | — | — | |
| SCHEMBL499165 | 0.71 | — | — | |
| SCHEMBL9305933 | 0.69 | — | — | |
| SCHEMBL5881384 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250069948-A1 | DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS | LAM RESEARCH CORPORATION (US) | 2025-02-27 | — | — | US | claimed |
| EP-4448831-A1 | DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS | Lam Research Corporation (US) | 2024-10-23 | — | — | EP | claimed |
| CN-118434908-A | Metal deposition in recessed features using halogen-containing deposition inhibitors | 朗姆研究公司 | 2024-08-02 | — | — | CN | claimed |
| CN-116874568-A | Synthesis method of valpromethazine | 中国人民解放军海军军医大学 | 2023-10-13 | — | — | CN | claimed |
| CN-116082648-B | Functionalized star-shaped solution polymerized styrene-butadiene rubber, preparation method thereof and application thereof in new energy automobile tires | 广东粤港澳大湾区黄埔材料研究院 | 2023-08-08 | — | — | CN | claimed |
| WO-2023114640-A1 | DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS | LAM RESEARCH CORPORATION (US) | 2023-06-22 | — | — | WO | claimed |
| CN-116082648-A | Functionalized star-shaped solution polymerized styrene-butadiene rubber, preparation method thereof and application thereof in new energy automobile tires | 广东粤港澳大湾区黄埔材料研究院 | 2023-05-09 | — | — | CN | claimed |
| CN-110256638-A | A kind of preparation method containing the polycarboxylate water-reducer that anti-mud structure is complexed | 江门市科锐新材料有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-109232222-A | A kind of preparation method of (E)-octyl- 4- alkene -1,8- diacid | 武汉嘉诺康医药技术有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-108299334-A | Double-ring sulfenyl amine-ene chiral ligand and preparation method and application | 成都理工大学 | 2018-07-20 | — | — | CN | claimed |
| CN-106008853-B | A kind of preparation method of anti-mud collapse protection type phosphate ester-containing based polycarboxylic acid water-reducing agent | 江苏中铁奥莱特新材料股份有限公司 | 2018-05-04 | — | — | CN | claimed |
| US-8987531-B2 | Syntheses of Z-olefin-containing lepidopteran insect pheromones | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-03-24 | — | — | US | claimed |
| EP-2838359-A1 | SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES | California Institute of Technology (US) | 2015-02-25 | — | — | EP | claimed |
| US-20130303748-A1 | METHOD FOR MAKING ALDEHYDE-FUNCTIONALIZED POLYSACCHARIDES | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2013-11-14 | — | — | US | claimed |
| WO-2013134192-A1 | SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-09-12 | — | — | WO | claimed |
| US-20130231499-A1 | SYNTHESIS OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2013-09-05 | — | — | US | claimed |
| CN-101182304-B | Method for preparing N-alkyl pyrrolidine | SHANDONG JINCHENG PHARMACEUTICAL CO LTD | 2010-05-12 | — | — | CN | claimed |
| CN-101182304-A | Method for preparing N-alkyl pyrrolidine | SHANDONG JINCHENG PHARMACEUTIC (CN) | 2008-05-21 | — | — | CN | claimed |
| US-3960566-A | Method for dry stabilization of silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | claimed |
| US-20260136848-A1 | DEPOSITION OF METAL-CONTAINING FILMS | LAM RES CORP (US) | 2026-05-14 | — | — | US | disclosed |
| US-12616576-B2 | Methods of modifying the porous surface of implants | BIOMET MANUFACTURING, LLC (US) | 2026-05-05 | — | — | US | disclosed |
| US-12605488-B2 | Surface treatment methods for cementless implantable medical devices | DURAHIP, LLC (US) | 2026-04-21 | — | — | US | disclosed |
| US-20250069948-A1 | DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS | LAM RESEARCH CORPORATION (US) | 2025-02-27 | — | — | US | disclosed |
| US-20240400520-A1 | 5-METHYL-6-PHENYL-4,5-DIHYDRO-2H-PYRIDAZIN-3-ONE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-12-05 | — | — | US | disclosed |
| EP-4448831-A1 | DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS | Lam Research Corporation (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118527068-A | Tubular reactor capable of continuously producing Grignard reagent | 吉林化工学院 | 2024-08-23 | — | — | CN | disclosed |
| CN-116063345-B | Phosphonic acid group monomer and preparation method thereof | 中国石油化工股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-118434908-A | Metal deposition in recessed features using halogen-containing deposition inhibitors | 朗姆研究公司 | 2024-08-02 | — | — | CN | disclosed |
| US-20240207482-A1 | SURFACE TREATMENT METHODS FOR CEMENTLESS IMPLANTABLE MEDICAL DEVICES | DURAHIP, LLC | 2024-06-27 | — | — | US | disclosed |
| CN-116063626-B | Anti-calcium shrinkage and expansion agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2024081263-A1 | DEPOSITION OF METAL-CONTAINING FILMS | LAM RESEARCH CORPORATION (US) | 2024-04-18 | — | — | WO | disclosed |
| CN-116064016-B | Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116874568-A | Synthesis method of valpromethazine | 中国人民解放军海军军医大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-116082648-B | Functionalized star-shaped solution polymerized styrene-butadiene rubber, preparation method thereof and application thereof in new energy automobile tires | 广东粤港澳大湾区黄埔材料研究院 | 2023-08-08 | — | — | CN | disclosed |
| CN-116478341-A | High-adaptability amphoteric phosphate-based water reducer and preparation method thereof | 广东苏博特新材料有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-11685702-B2 | Method for producing arene compounds and arene compounds produced by the same | JSI SILICONE CO. (KR) | 2023-06-27 | — | — | US | disclosed |
| WO-2023114640-A1 | DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS | LAM RESEARCH CORPORATION (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-116082648-A | Functionalized star-shaped solution polymerized styrene-butadiene rubber, preparation method thereof and application thereof in new energy automobile tires | 广东粤港澳大湾区黄埔材料研究院 | 2023-05-09 | — | — | CN | disclosed |
| CN-116063345-A | Phosphonic acid group monomer and preparation method thereof | 中国石油化工股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-116064016-A | Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-116063626-A | Anti-calcium shrinkage and expansion agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-3586882-B1 | ANTIBACTERIAL BIOLOGICAL IMPLANT | PROSTEC CO LTD (JP) | 2023-02-22 | — | — | EP | disclosed |
| US-20220331115-A1 | METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS | BIOMET MFG LLC (US) | 2022-10-20 | — | — | US | disclosed |
| US-11395740-B2 | Methods of modifying the porous surface of implants | BIOMET MANUFACTURING, LLC (US) | 2022-07-26 | — | — | US | disclosed |
| EP-3981444-A1 | METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS | Biomet Manufacturing, LLC (US) | 2022-04-13 | — | — | EP | disclosed |
| US-11289238-B2 | Compositions for the filling of high aspect ratio vertical interconnect access (VIA) holes | HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) | 2022-03-29 | — | — | US | disclosed |
| EP-3946604-A1 | BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | The Scripps Research Institute (US) | 2022-02-09 | — | — | EP | disclosed |
| US-20210188739-A1 | METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME | JSI SILICONE CO. (KR) | 2021-06-24 | — | — | US | disclosed |
| EP-3807369-A1 | FLUOROPOLYMER COMPOSITIONS COMPRISING FLUORINATED ADDITIVES, COATED SUBSTRATES AND METHODS | 3M Innovative Properties Company (US) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020205683-A1 | BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-10-08 | — | — | WO | disclosed |
| EP-3559105-A1 | COMPOSITION INCLUDING FLUOROPOLYMER AND INORGANIC FILLER AND METHOD OF MAKING A THREE-DIMENSIONAL ARTICLE | 3M Innovative Properties Company (US) | 2019-10-30 | — | — | EP | disclosed |
| EP-3541629-A1 | COMPOSITIONS INCLUDING POLYMER AND HOLLOW CERAMIC MICROSPHERES AND METHOD OF MAKING A THREE-DIMENSIONAL ARTICLE | 3M Innovative Properties Company (US) | 2019-09-25 | — | — | EP | disclosed |
| CN-110256638-A | A kind of preparation method containing the polycarboxylate water-reducer that anti-mud structure is complexed | 江门市科锐新材料有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-109694474-A | Organo-silicon compound, its manufacturing method and solidification compound | 信越化学工业株式会社 | 2019-04-30 | — | — | CN | disclosed |
| CN-109232222-A | A kind of preparation method of (E)-octyl- 4- alkene -1,8- diacid | 武汉嘉诺康医药技术有限公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-105339340-B | Generated base alkaline agent, the alkali reactive composition containing the generated base alkaline agent and production alkali method | 富士胶片和光纯药株式会社 | 2018-10-12 | — | — | CN | disclosed |
| EP-3365389-A1 | COMPOSITION INCLUDING AMORPHOUS FLUOROPOLYMER AND FLUOROPLASTIC PARTICLES AND METHODS OF MAKING THE SAME | 3M Innovative Properties Company (US) | 2018-08-29 | — | — | EP | disclosed |
| CN-104816104-B | Ag balls, Ag cores ball, scaling powder coating Ag balls, scaling powder coating Ag cores ball, solder joints, forming solder, soldering paste | 千住金属工业株式会社 | 2018-07-03 | — | — | CN | disclosed |
| WO-2018118956-A1 | COMPOSITION INCLUDING FLUOROPOLYMER AND INORGANIC FILLER AND METHOD OF MAKING A THREE-DIMENSIONAL ARTICLE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018094185-A1 | COMPOSITIONS INCLUDING POLYMER AND HOLLOW CERAMIC MICROSPHERES AND METHOD OF MAKING A THREE-DIMENSIONAL ARTICLE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |
| CN-106008853-B | A kind of preparation method of anti-mud collapse protection type phosphate ester-containing based polycarboxylic acid water-reducing agent | 江苏中铁奥莱特新材料股份有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107108615-A | Toll-like receptor modulating 4, 6-diamino-pyrido [3,2-D ] pyrimidine compounds | 吉利德科学公司 | 2017-08-29 | — | — | CN | disclosed |
| EP-3208287-A1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | Sirrus, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| WO-2017070172-A1 | COMPOSITION INCLUDING AMORPHOUS FLUOROPOLYMER AND FLUOROPLASTIC PARTICLES AND METHODS OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20170051053-A1 | METHOD OF PROVIDING MONOCLONAL AUTO-ANTIBODIES WITH DESIRED SPECIFICITY | IMMUNOQURE AG (DE) | 2017-02-23 | — | — | US | disclosed |
| EP-3114167-A1 | HIGHLY FLUORINATED ELASTOMERS | 3M Innovative Properties Company (US) | 2017-01-11 | — | — | EP | disclosed |
| US-9505976-B2 | Excitation-dependent fluorescent organic nanoparticles | NATIONAL KAOHSIUNG NORMAL UNIVERSITY (TW) | 2016-11-29 | — | — | US | disclosed |
| CN-106008853-A | Preparation method of mud resisting and slump retaining type phosphate group containing polycarboxylate superplasticizer | 江苏中铁奥莱特新材料股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105339340-A | Base generator, base-reactive composition containing said base generator, and base generation method | WAKO PURE CHEM IND LTD | 2016-02-17 | — | — | CN | disclosed |
| US-9227902-B2 | Compositions for carboxylic acid production and methods for making and using same | PRETIUM VENTURES AA, LLC (US) | 2016-01-05 | — | — | US | disclosed |
| US-9193715-B2 | Regulation of cholesterol homeostasis | UNIVERSITY OF NOTRE DAM DU LAC (US) | 2015-11-24 | — | — | US | disclosed |
| WO-2015134435-A1 | HIGHLY FLUORINATED ELASTOMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-11 | — | — | WO | disclosed |
| CN-104816104-A | Ag ball, Ag core ball, flux-coated Ag ball, flux-coated Ag core ball, solder joint, formed solder, solder paste | SENJU METAL INDUSTRY CO | 2015-08-05 | — | — | CN | disclosed |
| US-8987531-B2 | Syntheses of Z-olefin-containing lepidopteran insect pheromones | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-03-24 | — | — | US | disclosed |
| US-20150073515-A1 | Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods | Medtronic Ardian Luxembourg S.a.r.I. (LU) | 2015-03-12 | — | — | US | disclosed |
| EP-2838359-A1 | SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES | California Institute of Technology (US) | 2015-02-25 | — | — | EP | disclosed |
| US-20150038566-A1 | REGULATION OF CHOLESTEROL HOMEOSTASIS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-02-05 | — | — | US | disclosed |
| EP-2814485-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | Merck Sharp & Dohme Corp. (US) | 2014-12-24 | — | — | EP | disclosed |
| US-20140350296-A1 | COMPOSITIONS FOR CARBOXYLIC ACID PRODUCTION AND METHODS FOR MAKING AND USING SAME | PRETIUM VENTURES AA, LLC (US) | 2014-11-27 | — | — | US | disclosed |
| US-8865761-B1 | Regulation of cholesterol homeostasis | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 2014-10-21 | — | — | US | disclosed |
| CN-101522657-B | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-15 | — | — | CN | disclosed |
| EP-1957073-B1 | MEDICINAL DRUG | OTSUKA PHARMA CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| EP-2694571-A1 | FLUOROPOLYETHER ELASTOMER COMPOSITIONS HAVING LOW GLASS TRANSITION TEMPERATURES | 3M Innovative Properties Company (US) | 2014-02-12 | — | — | EP | disclosed |
| US-20130303748-A1 | METHOD FOR MAKING ALDEHYDE-FUNCTIONALIZED POLYSACCHARIDES | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2013-11-14 | — | — | US | disclosed |
| WO-2013134192-A1 | SYNTHESES OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-09-12 | — | — | WO | disclosed |
| US-20130231499-A1 | SYNTHESIS OF Z-OLEFIN-CONTAINING LEPIDOPTERAN INSECT PHEROMONES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2013-09-05 | — | — | US | disclosed |
| WO-2013122920-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME CORP. (US) | 2013-08-22 | — | — | WO | disclosed |
| EP-2612858-A1 | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-07-10 | — | — | EP | disclosed |
| EP-2601226-A1 | PEROXIDE CURABLE FLUOROELASTOMERS CONTAINING MODIFIERS AND IODINE OR BROMINE ENDGROUPS | 3M Innovative Properties Company (US) | 2013-06-12 | — | — | EP | disclosed |
| CN-1993339-B | Aromatic compound | OTSUKA PHARMA CO LTD | 2013-05-22 | — | — | CN | disclosed |
| US-20120322807-A1 | STAT3/5 ACTIVATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-12-20 | — | — | US | disclosed |
| CN-102786475-A | Proton exchange membrane monomer for fuel cell and synthesizing method thereof | UNIV SHANGHAI | 2012-11-21 | — | — | CN | disclosed |
| WO-2012138457-A1 | FLUOROPOLYETHER ELASTOMER COMPOSITIONS HAVING LOW GLASS TRANSITION TEMPERATURES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-10-11 | — | — | WO | disclosed |
| US-20120238750-A1 | AROMATIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-09-20 | — | — | US | disclosed |
| US-8263599-B2 | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8236826-B2 | Diarylether derivatives as antitumor agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-8188277-B2 | Aromatic compounds for suppressing the generation of collagen | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-05-29 | — | — | US | disclosed |
| EP-2445980-A2 | METHOD OF BONDING A FLUOROPOLYMER USING A SILANE CONTAINING BONDING PROMOTER | 3M Innovative Properties Company (US) | 2012-05-02 | — | — | EP | disclosed |
| WO-2012018603-A1 | PEROXIDE CURABLE FLUOROELASTOMERS CONTAINING MODIFIERS AND IODINE OR BROMINE ENDGROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |
| EP-2406240-A2 | INHIBITORS OF BETA-SECRETASE | Vitae Pharmaceuticals, Inc. (US) | 2012-01-18 | — | — | EP | disclosed |
| EP-2297080-A2 | COMPOSITIONS FOR CARBOXYLIC ACID PRODUCTION AND METHODS FOR MAKING AND USING SAME | Pretium Ventures AA, LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| US-7875638-B2 | desoxyepothilone A and B; Fludelone; anticarcinogenic agents; drug resistance; water solubility for formulability; industrial scale; cytotoxic or growth inhibitory effects on CAG myeloma cells lines; ability to polymerize tubulin; minimum toxicity; isomerization of the double bonds in the ring | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-01-25 | — | — | US | disclosed |
| WO-2011005443-A2 | METHOD OF BONDING A FLUOROPOLYMER USING A SILANE CONTAINING BONDING PROMOTER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-2271640-A2 | PIPERIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2011-01-12 | — | — | EP | disclosed |
| US-7834228-B1 | Synthesis of mono-substituted cyclopentadienes | BOULDER SCIENTIFIC COMPANY (US) | 2010-11-16 | — | — | US | disclosed |
| WO-2010105179-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-20100210661-A1 | STAT3/5 ACTIVATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-19 | — | — | US | disclosed |
| CN-101182304-B | Method for preparing N-alkyl pyrrolidine | SHANDONG JINCHENG PHARMACEUTICAL CO LTD | 2010-05-12 | — | — | CN | disclosed |
| US-20100004438-A1 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| WO-2009126530-A2 | CGRP RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-15 | — | — | WO | disclosed |
| US-20090149516-A1 | Synthesis of Epothilones, Intermediates Thereto, Analogues and Uses Thereof | DANISHEFSKY SAMUEL J | 2009-06-11 | — | — | US | disclosed |
| US-20090001501-A1 | Fiber Soi Substrate, Semiconductor Device Using Same and Method for Manufacturing Same | THE FURUKAWA ELECTRIC CO., LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2001883-A2 | AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | Merck & Co., Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| US-7384964-B2 | Synthesis of epothilones, intermediates thereto, analogues and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2008-06-10 | — | — | US | disclosed |
| CN-101182304-A | Method for preparing N-alkyl pyrrolidine | SHANDONG JINCHENG PHARMACEUTIC (CN) | 2008-05-21 | — | — | CN | disclosed |
| US-20070293540-A1 | for hepatitis C; histone deacetylase inhibitors; N-hydroxy-4-{[(naphthyl-carbonylamino]alkoxy}benzamides; anticarcinogenic agent; acute promyelocytic leukemia; cell-cycle arrest in late G1 phase or at the G2/M transition | PHARMACYCLICS, INC. | 2007-12-20 | — | — | US | disclosed |
| US-20070270422-A1 | Aromatic Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| WO-2007126745-A2 | AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| CN-101043937-A | Stirred tube reactor and method of use thereof | 3M INNOVATIVE PROPERTIES CO (US) | 2007-09-26 | — | — | CN | disclosed |
| EP-1722791-A2 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF | Sloan Kettering Institute For Cancer Research (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1704143-A1 | MALONONITRILE COMPOUND AS PESTICIDES | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-7022690-B2 | Carboxylic acid substituted heterocycles, derivatives thereof and methods of use | AMGEN INC. (US) | 2006-04-04 | — | — | US | disclosed |
| EP-1622606-A1 | QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS ANTIMUSCARINIC AGENTS | Pharmacia & Upjohn Company LLC (US) | 2006-02-08 | — | — | EP | disclosed |
| CN-1685010-A | Fluorinated polymers | 3M INNOVATIVE PROPERTIES CO (US) | 2005-10-19 | — | — | CN | disclosed |
| WO-2005084222-A2 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2005-09-15 | — | — | WO | disclosed |
| WO-2005068432-A1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-28 | — | — | WO | disclosed |
| US-20050159407-A1 | Carboxylic acid substituted heterocycles, derivatives thereof and methods of use | AMGEN INC. | 2005-07-21 | — | — | US | disclosed |
| US-20050143429-A1 | Synthesis of epothilones, intermediates thereto, analogues and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2005-06-30 | — | — | US | disclosed |
| US-20050066453-A1 | Photochromic dye | NEW PRISMATIC ENTERPRISE CO., LTD. (TW) | 2005-03-31 | — | — | US | disclosed |
| US-6838454-B2 | Carboxylic acid substituted heterocycles, derivatives thereof and methods of use | AMGEN INC. (US) | 2005-01-04 | — | — | US | disclosed |
| US-20040242569-A1 | Quatemary ammonium compounds | PFIZER INC. | 2004-12-02 | — | — | US | disclosed |
| WO-2004091607-A1 | QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS ANTIMUSCARINIC AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-10-28 | — | — | WO | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| US-20040029863-A1 | Carboxylic acid substituted heterocycles, derivatives thereof and methods of use | AMGEN INC. | 2004-02-12 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6593351-B2 | 3-Sulfonylamino-c5 to c8-methyleneimino-2-carboxylic acid compound is effective for prophylaxis and treatment of inflammation, tissue degradation, cancer, fibrosis and related diseases | AMGEN INC. | 2003-07-15 | — | — | US | disclosed |
| CN-1110482-C | Carboxyl acid substituted heterocycles as metalloproteinase inhibitors | AMGEN INC (US) | 2003-06-04 | — | — | CN | disclosed |
| US-6531602-B2 | Desilylation of a 2-pyridylsilane to form an alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-11 | — | — | US | disclosed |
| WO-2003018521-A1 | SUBSTITUTED ALKENE DIOLS | ISIS INNOVATION LIMITED (GB) | 2003-03-06 | — | — | WO | disclosed |
| EP-1042297-B1 | CARBOXYL ACID SUBSTITUTED HETEROCYCLES AS METALLOPROTEINASE INHIBITORS | AMGEN INC (US) | 2003-02-26 | — | — | EP | disclosed |
| WO-2002098935-A1 | COPOLYMERS OF $G(A)-OLEFINS AND OF FUNCTIONAL MONOMERS, THEIR PRODUCTION AND THE USE THEREOF | BOREALIS TECHNOLOGY OY (FI) | 2002-12-12 | — | — | WO | disclosed |
| US-20020165397-A1 | 2-Pyridylsilane, processes for producing and using the same | SUMITOMO CHEMICAL CO., LTD. | 2002-11-07 | — | — | US | disclosed |
| US-20020065269-A1 | Carboxylic acid substituted heterocycles, derivatives thereof and methods of use | AMGEN INC. | 2002-05-30 | — | — | US | disclosed |
| US-6335329-B1 | N-SULFONYL-3-AMINOAZEPINE-2-CARBOXYLIC ACID DERIVATIVES; ANTIINFLAMMATORY, ANTICARCINOGENIC, AND ANTIARTHRITIC AGENTS; METALLOPROTEINASE INHIBITORS | AMGEN INC. | 2002-01-01 | — | — | US | disclosed |
| US-6291450-B1 | Carboxylic acid substituted heterocycles, derivatives thereof and methods of use | AMGEN INC. | 2001-09-18 | — | — | US | disclosed |
| CN-1284947-A | Carboxyl acid substituted heterocycles as metalloproteinase inhibitors | AMGEN INC (US) | 2001-02-21 | — | — | CN | disclosed |
| EP-1052281-A1 | NOVEL ADDITIVE COMPOSITIONS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-6136759-A | OIL ADDITIVE COMPOSITION COMPRISING ESTER COMPOUND, EXTREME PRESSURE IMPROVER CONTAINING SULFUR AND IMPROVER CONTAINING PHOSPHORUS | IDEMITSU KOSAN CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1042297-A1 | CARBOXYL ACID SUBSTITUTED HETEROCYCLES AS METALLOPROTEINASE INHIBITORS | Amgen Inc. (US) | 2000-10-11 | — | — | EP | disclosed |
| EP-1040099-A1 | AZEPINE OR LARGER MEDIUM RING DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Amgen Inc., (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6107291-A | ANTIINFLAMMATORY AGENT | AMGEN INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0933347-A1 | Process for the preparation of a carboxylic acid | DSM N.V. (NL) | 1999-08-04 | — | — | EP | disclosed |
| WO-1999033779-A1 | PROCESS FOR THE PREPARATION OF A CARBOXYLIC ACID | DSM N.V. (NL) | 1999-07-08 | — | — | WO | disclosed |
| WO-1999032451-A1 | AZEPINE OR LARGER MEDIUM RING DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | AMGEN INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999032452-A1 | CARBOXYL ACID SUBSTITUTED HETEROCYCLES AS METALLOPROTEINASE INHIBITORS | AMGEN INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0912477-A1 | PROCESS FOR THE PREPARATION OF 2-ALKENE-1,4-DIOLS AND 3-ALKENE-1,2-DIOLS FROM $g(g),$g(d)-EPOXYALKENES | EASTMAN CHEMICAL COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0912478-A1 | PROCESS FOR THE SEPARATION OF 2-ALKENE-1,4-DIOLS AND 3-ALKENE-1, 2-DIOLS FROM CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1999011592-A1 | PROCESS FOR THE PREPARATION OF 1,4-BUTENEDIOL FROM EPOXYBUTENE | THE DOW CHEMICAL COMPANY (US) | 1999-03-11 | — | — | WO | disclosed |
| WO-1998002405-A9 | PROCESS FOR THE SEPARATION OF 2-ALKENE-1,4-DIOLS AND 3-ALKENE-1, 2-DIOLS FROM CATALYSTS | — | 1998-06-04 | — | — | WO | disclosed |
| EP-0837728-A1 | SUPPORTED CARBONYLATION CATALYST | DSM N.V. (NL) | 1998-04-29 | — | — | EP | disclosed |
| WO-1998002405-A1 | PROCESS FOR THE SEPARATION OF 2-ALKENE-1,4-DIOLS AND 3-ALKENE-1, 2-DIOLS FROM CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 1998-01-22 | — | — | WO | disclosed |
| WO-1998002404-A1 | PROCESS FOR THE PREPARATION OF 2-ALKENE-1,4-DIOLS AND 3-ALKENE-1,2-DIOLS FROM η,δ-EPOXYALKENES | EASTMAN CHEMICAL COMPANY (US) | 1998-01-22 | — | — | WO | disclosed |
| WO-1997002091-A1 | SUPPORTED CARBONYLATION CATALYST | DSM N.V. (NL) | 1997-01-23 | — | — | WO | disclosed |
| US-5235061-A | 2,4-disilaalkanes; agriculture | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-08-10 | — | — | US | disclosed |
| EP-0224794-B1 | CYCLIC AMINE DERIVATIVES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |
| US-4680414-A | Substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones | MERCK & CO., INC. (US) | 1987-07-14 | — | — | US | disclosed |
| US-4634717-A | BRIAN INJURY | MERCK & CO., INC. (US) | 1987-01-06 | — | — | US | disclosed |
| US-4605663-A | BRAIN TRAUMA | MERCK & CO., INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4605664-A | BRAIN TRAUMA | MERCK & CO., INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4604403-A | Use of substituted-3(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones for treating grey matter edema | MERCK & CO., INC. (US) | 1986-08-05 | — | — | US | disclosed |
| US-4596821-A | Brain disorders | MERCK & CO., INC. (US) | 1986-06-24 | — | — | US | disclosed |
| US-4593096-A | Novel compounds and process for treating hypertension | THE UPJOHN COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0160891-A1 | Substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-Hydroxy-1H-Pyrrole-2,5-diones, their analogs and their salts | MERCK & CO. INC. (US) | 1985-11-13 | — | — | EP | disclosed |
| EP-0141608-A2 | Pyrazolopyridine cycloalkanone derivatives | ICI AMERICAS INC. (US) | 1985-05-15 | — | — | EP | disclosed |
| EP-0008457-B1 | PREPARATION OF FURAN COMPOUNDS AND CATALYST SYSTEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |
| US-4460589-A | 2-AMINO-5-HALO-6-PHENYL-4-PYRIMIDINONES | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0057736-A1 | Olefin disproportionation process and catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1982-08-18 | — | — | EP | disclosed |
| US-4268421-A | OXIDATION CATALYST OF ALKALI METAL IODIDE, CUPRIC OR CUPROUS SALT, SOLUBILIZER, WATER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-19 | — | — | US | disclosed |
| EP-0008457-A2 | Preparation of furan compounds and catalyst system | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-03-05 | — | — | EP | disclosed |
| US-4172838-A | CATALYTIC OXIDATION OF A CONJUGATED DIOLEFIN OR A HALO-SUBSTITUTED ALKENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4101557-A | DEHYDROHALOGENATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-07-18 | — | — | US | disclosed |
| US-3960566-A | Method for dry stabilization of silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | disclosed |
| US-3960566-A | Method for dry stabilization of silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | disclosed |