SCHEMBL4754036

SCHEMBL4754036

C/C=C\CI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28074 1.00
SCHEMBL5675955 1.00
SCHEMBL11742784 0.96
SCHEMBL16977137 0.74
SCHEMBL1556924 0.72 TSHR (0.33)
SCHEMBL499166 0.71
SCHEMBL3434947 0.71
SCHEMBL499165 0.71
SCHEMBL9305933 0.69
SCHEMBL5881384 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2580201-B1 TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF RHODES TECH (US) 2017-08-02 EP disclosed
US-9570706-B2 Organic light-emitting diode (OLED) display having a plurality of spacers covering one or more via holes SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-02-14 US disclosed
EP-2411009-B1 Therapeutic uses of quinazolinedione derivatives SANOFI SA (FR) 2013-03-20 EP disclosed
US-7993641-B2 Methods of treatment using anti-CD3 antibodies BTG INTERNATIONAL LIMITED (GB) 2011-08-09 US disclosed
EP-2001883-A2 AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES Merck & Co., Inc. (US) 2008-12-17 EP disclosed
US-20080009500-A1 Alpha-helix mimetics and methods relating to the treatment of fibrotic disorders INSTITUTE FOR CHEMICAL GENOMICS 2008-01-10 US disclosed
WO-2007126745-A2 AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES MERCK & CO., INC. (US) 2007-11-08 WO disclosed
US-20070092516-A1 Antibody preparation BTG INTERNATIONAL LIMITED (GB) 2007-04-26 US disclosed
EP-1622606-A1 QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS ANTIMUSCARINIC AGENTS Pharmacia & Upjohn Company LLC (US) 2006-02-08 EP disclosed
US-20040242569-A1 Quatemary ammonium compounds PFIZER INC. 2004-12-02 US disclosed
WO-2004091607-A1 QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS ANTIMUSCARINIC AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2004-10-28 WO disclosed