Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28077647 | 0.85 | TSHR (0.42) | HSD17B10TDP1USP2TSHR | |
| SCHEMBL7733969 | 0.83 | HSD17B10 (0.41) | HSD17B10TDP1TSHR | |
| SCHEMBL14895459 | 0.77 | HSD17B10 (0.39) | HSD17B10TDP1USP2TSHR | |
| Propylene Glycol SCHEMBL3193750 | 0.77 | TDP1 (0.59) | HSD17B10TDP1USP2TSHR | |
| Propanol SCHEMBL20640058 | 0.72 | HSD17B10 (0.54) | HSD17B10TDP1USP2TSHR | |
| Propylene Glycol SCHEMBL6390820 | 0.72 | TDP1 (0.53) | HSD17B10TDP1USP2TSHR | |
| Alcohol SCHEMBL3425526 | 0.72 | — | — | |
| Butanol SCHEMBL3651611 | 0.72 | TSHR (0.59) | HSD17B10TDP1TSHR | |
| SCHEMBL7171050 | 0.71 | TSHR (0.34) | HSD17B10TDP1USP2TSHR | |
| SCHEMBL11153783 | 0.71 | LMNA (0.37) | HSD17B10TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429632-B | multifunctional epoxy compound | 日产化学工业株式会社 | 2016-07-06 | — | — | CN | disclosed |