Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1510191 | 0.88 | AAK1 (0.46) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL18861700 | 0.82 | CA12 (0.41) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL30951504 | 0.81 | AAK1 (0.47) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL28280979 | 0.79 | CA12 (0.42) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL28282423 | 0.78 | CA12 (0.43) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL31629681 | 0.77 | CA12 (0.39) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL28838138 | 0.75 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL31332036 | 0.74 | IDO1 (0.43) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL22718344 | 0.74 | IDO1 (0.43) | CA12CA14CA1CA7BRS3 | |
| SCHEMBL30817562 | 0.74 | IDO1 (0.43) | CA12CA14CA1CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109526219-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-105611923-B | Sodium channel modulators for the treatment of pain and diabetes | 卓莫赛尔公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-104093716-B | Biaryl ether sulfonamide compounds and its purposes as therapeutic agent | 克赛农制药股份有限公司 | 2017-06-23 | — | — | CN | disclosed |
| CN-105611923-A | Sodium channel modulators for the treatment of pain and diabetes | CHROMOCELL CORP | 2016-05-25 | — | — | CN | disclosed |