Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1510191 | 0.82 | AAK1 (0.46) | AAK1NPC1RAB9AALDH1A1CA12 | |
| SCHEMBL28074602 | 0.81 | SLC1A3 (0.42) | AAK1CA12CA1CA7CA14 | |
| SCHEMBL31172709 | 0.80 | GLA (0.57) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL18861700 | 0.78 | CA12 (0.41) | AAK1CA12CA1CA7CA14 | |
| SCHEMBL28282423 | 0.78 | CA12 (0.43) | ALDH1A1CA12CA1CA7CA14 | |
| SCHEMBL4432604 | 0.78 | EGFR (0.50) | NPC1RECQLRAB9ASMN1; SMN2CA12 | |
| SCHEMBL31629681 | 0.77 | CA12 (0.39) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL24757343 | 0.77 | CA12 (0.39) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL30781615 | 0.77 | CA12 (0.39) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL22718344 | 0.77 | IDO1 (0.43) | AAK1ALDH1A1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630428-A1 | COMPOUNDS FOR TREATING CANCER | Genesis Therapeutics, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024123801-A1 | COMPOUNDS FOR TREATING CANCER | GENESIS THERAPEUTICS, INC. (US) | 2024-06-13 | — | — | WO | disclosed |