Triphosphate

SCHEMBL28074755

O=P(O)(O)OP(=O)(O)OP(=O)(O)O.O=c1ccn([C@]2(F)O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.49

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY6	Q15077	11/20	0.49

▸	POLA1	P09884	1/20	0.48

▸	P2RY2	P41231	9/20	0.48

▸	P2RY4	P51582	5/20	0.47

▸	P2RY14	Q15391	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Pyrophosphoric Acid SCHEMBL2800166	0.96	P2RY6 (0.46)	P2RY6POLA1P2RY2P2RY4P2RY14
Phosphoric Acid SCHEMBL607047	0.91	SLC28A1 (0.45)	P2RY6P2RY2P2RY4P2RY14
Phosphoric Acid SCHEMBL2176024	0.91	SLC28A1 (0.45)	P2RY6P2RY2P2RY4P2RY14
SCHEMBL98410	0.89	SLC28A1 (0.49)	P2RY6P2RY2P2RY4P2RY14
SCHEMBL607049	0.89	POLA1 (0.60)	P2RY6POLA1P2RY2P2RY4
SCHEMBL2800175	0.89	P2RY6 (0.58)	P2RY6POLA1P2RY2P2RY4P2RY14
Water SCHEMBL27625510	0.88	SLC28A1 (0.48)	P2RY6P2RY2P2RY4P2RY14
Hydrochloric Acid SCHEMBL10584588	0.88	SLC28A1 (0.48)	P2RY6P2RY2P2RY4P2RY14
SCHEMBL2176031	0.84	P2RY6 (0.47)	P2RY6POLA1P2RY2P2RY4P2RY14
SCHEMBL29408563	0.83	P2RY6 (0.42)	P2RY6POLA1P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-105829334-B	Uracil nucleotides are like object and its preparation method and application	江苏豪森药业集团有限公司	2019-03-08	—	—	CN	disclosed
CN-105829334-A	Uracil nucleotide analogs, preparation methods therefor and uses thereof	江苏豪森药业集团有限公司	2016-08-03	—	—	CN	disclosed