SCHEMBL607049

SCHEMBL607049

O=c1ccn([C@]2(F)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.60
P2RY2 P41231 11/20 0.57
P2RY4 P51582 7/20 0.57
P2RY6 Q15077 13/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2800175 0.98 P2RY6 (0.58) POLA1P2RY2P2RY4P2RY6
SCHEMBL2176031 0.90 P2RY6 (0.47) POLA1P2RY2P2RY4P2RY6
Triphosphate SCHEMBL28074755 0.89 P2RY6 (0.49) POLA1P2RY2P2RY4P2RY6
SCHEMBL31398378 0.87 POLA1 (0.57) POLA1P2RY2P2RY4P2RY6
SCHEMBL2011098 0.87 P2RY2 (0.62) POLA1P2RY2P2RY4P2RY6
SCHEMBL30423444 0.87 P2RY2 (0.60) POLA1P2RY2P2RY4P2RY6
SCHEMBL30367562 0.86 P2RY2 (0.57) POLA1P2RY2P2RY4P2RY6
SCHEMBL34463723 0.86 P2RY14 (0.45) POLA1P2RY2P2RY4P2RY6
SCHEMBL31381447 0.85 P2RY14 (0.56) POLA1P2RY2P2RY4P2RY6
SCHEMBL18486642 0.85 P2RY6 (0.59) POLA1P2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080150-A Mutant of L protein of rift valley fever virus and application thereof 2026-05-26 CN disclosed
US-20260130950-A1 METHODS OF DELIVERY OF ISLET CELLS AND RELATED METHODS SANA BIOTECHNOLOGY INC (US) 2026-05-14 US disclosed
WO-2026090505-A1 FLUOROPYRIMIDINE PARTICLES FOR THE TREATMENT OF CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2026-04-30 WO disclosed
EP-4716541-A2 METHODS OF DELIVERY OF ISLET CELLS AND RELATED METHODS Sana Biotechnology, Inc. (US) 2026-04-01 EP disclosed
EP-4704867-A1 METHODS OF DOSING AND ADMINISTRATION OF ENGINEERED ISLET CELLS Sana Biotechnology, Inc. (US) 2026-03-11 EP disclosed
US-20260048086-A1 METHODS OF DOSING AND ADMINISTRATION OF ENGINEERED ISLET CELLS SANA BIOTECHNOLOGY INC (US) 2026-02-19 US disclosed
US-20260028622-A1 RNA NANOSTRUCTURES WITH BASE MODIFICATIONS FOR REDUCING INNATE IMMUNOGENICITY ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-01-29 US disclosed
US-20250360157-A1 CYTOTOXIC FLUOROPYRIMIDINE POLYMERS AND METHODS OF USE THEREOF Wake Forest Univesity Health Sciences (US) 2025-11-27 US disclosed
EP-4642443-A1 TREATMENT OF CANCER WITH A COMBINATION OF AN ANTIBODY THAT BINDS EGFR AND CYTOTOXIC DRUGS Merus N.V. (NL) 2025-11-05 EP disclosed
US-20250333476-A1 ENGINEERED CD47 PROTEINS AND USES THEREOF SANA BIOTECHNOLOGY INC (US) 2025-10-30 US disclosed
WO-2005046516-A2 MEDICAL IMPLANTS AND ANTI-SCARRING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-26 WO disclosed
WO-2005046746-A2 MEDICAL IMPLANTS AND FIBROSIS-INDUCING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-26 WO disclosed
WO-2005044142-A2 INTRAVASCULAR DEVICES AND FIBROSIS-INDUCING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-19 WO disclosed
US-20040265368-A1 Combination compositions of camptothecins and fluoropyrimidines CELATOR PHARMACEUTICALS, INC. 2004-12-30 US disclosed
WO-2004087115-A2 COMBINATION COMPOSITIONS OF CAMPTOTHECINS AND FLUOROPYRIMIDINES CELATOR PHARMACEUTICALS, INC. (US) 2004-10-14 WO disclosed
WO-2004087105-A1 COMBINATION FORMULATIONS OF PLATINUM AGENTS AND FLUOROPYRIMIDINES CELATOR PHARMACEUTICALS, INC. (US) 2004-10-14 WO disclosed
EP-0561303-B1 Conjugates of phenylalanine-glycine with antitumor substances KUREHA CHEMICAL IND CO LTD (JP) 1997-02-26 EP disclosed
US-5470960-A Antitumor agents KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-11-28 US disclosed
US-5411964-A Phenylalanine-glycine compounds having anti-tumor activity, process for preparation thereof, and pharmaceutical composition containing said compounds KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-05-02 US disclosed
EP-0561303-A2 Conjugates of phenylalanine-glycine with antitumor substances KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1993-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360157-A1 CYTOTOXIC FLUOROPYRIMIDINE POLYMERS AND METHODS OF USE THEREOF DPYD, DUT, UNG POLA1 226/4885P2RY2 3816/4885P2RY4 3497/4885
US-20260048086-A1 METHODS OF DOSING AND ADMINISTRATION OF ENGINEERED ISLET CELLS CD47, IAPP, HBG1 POLA1 4852/4885P2RY2 3422/4885P2RY4 3901/4885
US-20260028622-A1 RNA NANOSTRUCTURES WITH BASE MODIFICATIONS FOR REDUCING INNATE IMMUNOGENICITY NSUN3, TARBP1, TRDMT1 POLA1 354/4885P2RY2 4550/4885P2RY4 4226/4885
US-20260130950-A1 METHODS OF DELIVERY OF ISLET CELLS AND RELATED METHODS IAPP, GLP1R, PNLIP POLA1 4790/4885P2RY2 950/4885P2RY4 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.